Sister chromatid exchanges in the lymphocytes of patients with oral leukoplakia. - Suppr | 超能文献

Sister chromatid exchanges in the lymphocytes of patients with oral leukoplakia.

作者信息

Ghosh R, Sharma J K, Ghosh P K

机构信息

Department of Anthropology, University of Delhi, India.

出版信息

Cancer Genet Cytogenet. 1988 Dec;36(2):177-82. doi: 10.1016/0165-4608(88)90142-2.

DOI:10.1016/0165-4608(88)90142-2

Abstract

The incidence of sister chromatid exchange (SCE) was investigated in lymphocyte chromosomes of 59 patients with oral leukoplakia and 65 age- and sex-matched nonsmoking controls. The frequency of SCE was found to be 8.61 +/- 1.89 in patients with oral leukoplakia, which was significantly higher than the mean SCE value of 5.58 +/- 1.26 observed in normal controls. The frequency of SCE in patients with oral leukoplakia addicted to the single habit of betel with tobacco chewing, bidi/cigarette smoking, and combined habits of chewing and smoking of tobacco were found to be 7.95 +/- 1.63, 8.17 +/- 1.66, and 9.23 +/- 2.14, respectively. These values were also significantly higher as compared to the SCE values observed in normal controls.

摘要

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