Muthiah Mark D, Sanyal Arun J
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Drive, Singapore 117597; Division of Gastroenterology and Hepatology, National University Hospital, National University Health System, 1E Kent Ridge Road, Level 10 Tower Block, 119228, Singapore.
Department of Internal Medicine, Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University School of Medicine, MCV Box 980341, Richmond, VA 23298-0341, USA.
Gastroenterol Clin North Am. 2020 Mar;49(1):1-23. doi: 10.1016/j.gtc.2019.09.007.
Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most common liver disease in both Western populations and other parts of the world. This review discusses the prevalence and incidence of NAFLD in various regions around the world. The methodology used to identify the epidemiology and classify the stages of the disease is described. The impact of the disease on individuals, looking at both liver-related and extrahepatic consequences of the disease, is then discussed. Finally, the economic and societal impact of the disease is discussed.
非酒精性脂肪性肝病(NAFLD)正迅速成为西方人群以及世界其他地区最常见的肝脏疾病。本综述讨论了世界各地不同地区NAFLD的患病率和发病率。描述了用于确定该疾病流行病学和分类疾病阶段的方法。接着讨论了该疾病对个体的影响,包括与肝脏相关的后果和肝外后果。最后,讨论了该疾病的经济和社会影响。