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肘骨软骨骨软骨炎病变:骨软骨移植物重建选择的系统评价。

Capitellar Osteochondritis Dissecans Lesions of the Elbow: A Systematic Review of Osteochondral Graft Reconstruction Options.

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, U.S.A.

Division of Health Care Policy and Research, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, U.S.A.

出版信息

Arthroscopy. 2020 Jun;36(6):1747-1764. doi: 10.1016/j.arthro.2020.01.037. Epub 2020 Feb 6.

Abstract

PURPOSE

To systematically evaluate the outcomes and complications of osteochondral autograft transfer (OAT) and osteochondral allograft transplantation (OCA) for the surgical treatment of capitellar osteochondritis dissecans (OCD).

METHODS

A literature search was conducted across 3 databases (PubMed, Cochrane, and CINAHL [Cumulative Index to Nursing and Allied Health Literature]) from database inception through December 2019 in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Individual study quality was assessed using the Methodological Index for Non-randomized Studies scale. Studies were published between 2005 and 2019.

RESULTS

Eighteen studies consisting of 446 elbow OCD lesions treated with OAT surgery were included. There was a single OCA study eligible for inclusion. Patient ages ranged from 10 to 45 years. Of the OAT studies, 4 used autologous costal grafts whereas the remainder used autografts from the knee. Outcome measures were heterogeneously reported. A significant improvement in Timmerman-Andrews scores from preoperatively to postoperatively was reported in 9 of 10 studies. Return-to-play rates to the preinjury level of competitive play ranged from 62% to 100% across 16 studies. Significant improvement in motion, most often extension, was noted in most studies. Reported complication, reoperation, and failure rates ranged from 0% to 11%, 0% to 26%, and 0% to 20%, respectively. When used, knee autografts resulted in low donor-site morbidity (Lysholm scores, 70-100).

CONCLUSIONS

OAT surgery for large, unstable OCD lesions of the capitellum reliably produced good outcomes, few complications, and a high rate of return to competitive play. Complications are relatively uncommon, and donor-site morbidity is low. Less is known about the performance of OCA given the paucity of available literature.

LEVEL OF EVIDENCE

Level IV, systematic review of Level II to IV studies.

摘要

目的

系统评估骨软骨自体移植(OAT)和骨软骨同种异体移植(OCA)治疗骺骨软骨骨软骨炎(OCD)的手术治疗的结果和并发症。

方法

根据系统评价和荟萃分析的首选报告项目(PRISMA)指南,从数据库成立到 2019 年 12 月,在 3 个数据库(PubMed、Cochrane 和 Cumulative Index to Nursing and Allied Health Literature [CINAHL])中进行了文献检索。使用非随机研究方法学指数量表评估个别研究质量。研究发表于 2005 年至 2019 年之间。

结果

纳入了 18 项研究,共 446 例肘 OCD 病变接受 OAT 手术治疗。有一项符合纳入标准的 OCA 研究。患者年龄在 10 至 45 岁之间。在 OAT 研究中,4 项研究使用了自体肋软骨移植物,其余研究则使用了来自膝关节的自体移植物。结果指标的报道存在异质性。10 项研究中有 9 项报告了术前至术后 Timmerman-Andrews 评分的显著改善。在 16 项研究中,重返术前竞技运动水平的比例从 62%到 100%不等。大多数研究中都注意到运动(通常是伸展)的显著改善。报告的并发症、再次手术和失败率分别为 0%至 11%、0%至 26%和 0%至 20%。当使用膝关节自体移植物时,其导致的供体部位发病率较低(Lysholm 评分,70-100)。

结论

对于大的、不稳定的肱骨小头 OCD 病变,OAT 手术可可靠地产生良好的结果、较少的并发症和较高的重返竞技运动的比例。并发症相对少见,供体部位发病率较低。鉴于现有文献的缺乏,对于 OCA 的表现了解较少。

证据等级

IV 级,对 II 级至 IV 级研究的系统评价。

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