Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, U.S.A.
Division of Health Care Policy and Research, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, U.S.A.
Arthroscopy. 2020 Jun;36(6):1747-1764. doi: 10.1016/j.arthro.2020.01.037. Epub 2020 Feb 6.
To systematically evaluate the outcomes and complications of osteochondral autograft transfer (OAT) and osteochondral allograft transplantation (OCA) for the surgical treatment of capitellar osteochondritis dissecans (OCD).
A literature search was conducted across 3 databases (PubMed, Cochrane, and CINAHL [Cumulative Index to Nursing and Allied Health Literature]) from database inception through December 2019 in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Individual study quality was assessed using the Methodological Index for Non-randomized Studies scale. Studies were published between 2005 and 2019.
Eighteen studies consisting of 446 elbow OCD lesions treated with OAT surgery were included. There was a single OCA study eligible for inclusion. Patient ages ranged from 10 to 45 years. Of the OAT studies, 4 used autologous costal grafts whereas the remainder used autografts from the knee. Outcome measures were heterogeneously reported. A significant improvement in Timmerman-Andrews scores from preoperatively to postoperatively was reported in 9 of 10 studies. Return-to-play rates to the preinjury level of competitive play ranged from 62% to 100% across 16 studies. Significant improvement in motion, most often extension, was noted in most studies. Reported complication, reoperation, and failure rates ranged from 0% to 11%, 0% to 26%, and 0% to 20%, respectively. When used, knee autografts resulted in low donor-site morbidity (Lysholm scores, 70-100).
OAT surgery for large, unstable OCD lesions of the capitellum reliably produced good outcomes, few complications, and a high rate of return to competitive play. Complications are relatively uncommon, and donor-site morbidity is low. Less is known about the performance of OCA given the paucity of available literature.
Level IV, systematic review of Level II to IV studies.
系统评估骨软骨自体移植(OAT)和骨软骨同种异体移植(OCA)治疗骺骨软骨骨软骨炎(OCD)的手术治疗的结果和并发症。
根据系统评价和荟萃分析的首选报告项目(PRISMA)指南,从数据库成立到 2019 年 12 月,在 3 个数据库(PubMed、Cochrane 和 Cumulative Index to Nursing and Allied Health Literature [CINAHL])中进行了文献检索。使用非随机研究方法学指数量表评估个别研究质量。研究发表于 2005 年至 2019 年之间。
纳入了 18 项研究,共 446 例肘 OCD 病变接受 OAT 手术治疗。有一项符合纳入标准的 OCA 研究。患者年龄在 10 至 45 岁之间。在 OAT 研究中,4 项研究使用了自体肋软骨移植物,其余研究则使用了来自膝关节的自体移植物。结果指标的报道存在异质性。10 项研究中有 9 项报告了术前至术后 Timmerman-Andrews 评分的显著改善。在 16 项研究中,重返术前竞技运动水平的比例从 62%到 100%不等。大多数研究中都注意到运动(通常是伸展)的显著改善。报告的并发症、再次手术和失败率分别为 0%至 11%、0%至 26%和 0%至 20%。当使用膝关节自体移植物时,其导致的供体部位发病率较低(Lysholm 评分,70-100)。
对于大的、不稳定的肱骨小头 OCD 病变,OAT 手术可可靠地产生良好的结果、较少的并发症和较高的重返竞技运动的比例。并发症相对少见,供体部位发病率较低。鉴于现有文献的缺乏,对于 OCA 的表现了解较少。
IV 级,对 II 级至 IV 级研究的系统评价。