Istanbul University, Istanbul Medical Faculty, Orthopedics and Traumatology Department, Turkey.
Istanbul University, Istanbul Medical Faculty, Orthopedics and Traumatology Department, Turkey.
Foot (Edinb). 2020 Mar;42:101649. doi: 10.1016/j.foot.2019.10.004. Epub 2019 Oct 24.
Osteonecrosis (ON) is a disabling complication of acute lymphoblastic leukemia (ALL) treatment in children and young adults. Isolated talus involvement is thought to be uncommon. A unique case of a 11-year-old female patient with ON in her left talus which developed six months after the completion of chemotherapy that she received for ALL is reported. A conservative treatment protocol was followed including activity modification, analgesia and prevention of weight-bearing. However, the disease significantly progressed during follow-up period. The present study makes an important contribution to the literature with unusual involvement pattern and location of ON after ALL treatment and with a long follow-up duration. LEVEL OF EVIDENCE: IV.
骨坏死（ON）是儿童和青年急性淋巴细胞白血病（ALL）治疗的一种致残并发症。孤立性距骨受累被认为并不常见。报告了一例独特的 11 岁女性患者，她在 ALL 化疗完成后 6 个月发生左侧距骨 ON。采用了包括活动方式改变、止痛和避免负重的保守治疗方案。然而，疾病在随访期间显著进展。本研究对 ALL 治疗后罕见的 ON 累及模式和部位以及长期随访的病例做出了重要贡献。证据等级：IV。
