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抗菌药物管理计划使一家退伍军人医院的艰难梭菌感染显著减少。

Antimicrobial stewardship program achieved marked decrease in Clostridium difficile infections in a Veterans Hospital.

作者信息

Morgan Froehlich, Belal Maymonah, Lisa Bailey, Ford Florence, LeMaitre Beth, Psevdos George

机构信息

Department of Pharmacy, Veterans Affairs Medical Center, Northport NY.

Department of Infectious Diseases, Stony Brook University Hospital, Stony Brook, NY.

出版信息

Am J Infect Control. 2020 Sep;48(9):1119-1121. doi: 10.1016/j.ajic.2019.12.023. Epub 2020 Feb 6.

DOI:10.1016/j.ajic.2019.12.023
PMID:32035688
Abstract

Clostridium (or Clostridioides) difficile infection (CDI) is a common side effect of antimicrobial therapy and is increasingly linked with health care-associated transmissions. Antimicrobial stewardship programs (ASP) have demonstrated success in decreasing in-hospital CDI cases. We implemented an ASP targeting inappropriate or unnecessary use of all antibiotics especially empiric piperacillin-tazobactam and fluoroquinolone use. Concurrently, we monitored all health-care associated CDI. Our CDI cases were markedly decreased after initiation of our ASP.

摘要

艰难梭菌感染（CDI）是抗菌治疗的常见副作用，且越来越多地与医疗保健相关传播有关。抗菌药物管理计划（ASP）已证明在减少医院内CDI病例方面取得了成功。我们实施了一项针对所有抗生素不适当或不必要使用的ASP，特别是经验性使用哌拉西林-他唑巴坦和氟喹诺酮类药物。同时，我们监测了所有与医疗保健相关的CDI。在我们的ASP启动后，我们的CDI病例显著减少。

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