• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

牙髓间充质干细胞:对抗糖尿病的潜在有力武器。

Wharton's Jelly MSCs: Potential Weapon to Sharpen for Our Battle against DM.

机构信息

Department of Biochemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Department of Biochemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt; Department of Pharmacology and Biochemistry, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo, Egypt; The Center for Drug Research and Development (CDRD), Faculty of Pharmacy, The British University in Egypt (BUE), Cairo, Egypt.

出版信息

Trends Endocrinol Metab. 2020 Apr;31(4):271-273. doi: 10.1016/j.tem.2020.01.001. Epub 2020 Feb 5.

DOI:10.1016/j.tem.2020.01.001
PMID:32035737
Abstract

Diabetes mellitus (DM) is a devastating metabolic disease. Stem cell therapy provides great hope to all diabetic patients. Umbilical cord (UC) Wharton's jelly mesenchymal stem cells (WJ-MSCs) specifically provides a potential cell therapy for DM. In this article, we discuss major advantages of WJ-MSCs and challenges facing their clinical utility in DM.

摘要

糖尿病(DM)是一种毁灭性的代谢性疾病。干细胞疗法为所有糖尿病患者带来了巨大的希望。脐带(UC)Wharton 胶间充质干细胞(WJ-MSCs)特别为 DM 提供了一种潜在的细胞治疗方法。在本文中,我们讨论了 WJ-MSCs 的主要优势及其在 DM 临床应用中面临的挑战。

相似文献

1
Wharton's Jelly MSCs: Potential Weapon to Sharpen for Our Battle against DM.牙髓间充质干细胞:对抗糖尿病的潜在有力武器。
Trends Endocrinol Metab. 2020 Apr;31(4):271-273. doi: 10.1016/j.tem.2020.01.001. Epub 2020 Feb 5.
2
Therapeutic efficacy of umbilical cord-derived stem cells for diabetes mellitus: a meta-analysis study.脐带间充质干细胞治疗糖尿病的疗效:一项荟萃分析研究。
Stem Cell Res Ther. 2020 Nov 16;11(1):484. doi: 10.1186/s13287-020-01996-x.
3
A comparison of Wharton's jelly and cord blood as a source of mesenchymal stem cells for diabetes cell therapy.比较脐带胶质和脐带血作为间充质干细胞来源用于糖尿病细胞治疗的情况。
Regen Med. 2015;10(7):841-55. doi: 10.2217/rme.15.49. Epub 2015 Nov 6.
4
Mesenchymal Stem Cells from Wharton's Jelly and Amniotic Fluid.来自脐带华通氏胶和羊水的间充质干细胞。
Best Pract Res Clin Obstet Gynaecol. 2016 Feb;31:30-44. doi: 10.1016/j.bpobgyn.2015.07.006. Epub 2015 Sep 10.
5
Human Wharton's jelly mesenchymal stem cells: properties, isolation and clinical applications.人牙髓间充质干细胞:特性、分离和临床应用。
J Biol Regul Homeost Agents. 2019;33(1):119-123.
6
Efficacy of FeO@polydopamine nanoparticle-labeled human umbilical cord Wharton's jelly-derived mesenchymal stem cells in the treatment of streptozotocin-induced diabetes in rats.FeO@聚多巴胺纳米颗粒标记的人脐带华通氏胶间充质干细胞治疗链脲佐菌素诱导的大鼠糖尿病的疗效
Biomater Sci. 2020 Oct 7;8(19):5362-5375. doi: 10.1039/d0bm01076f. Epub 2020 Sep 1.
7
Intravenous vs intraperitoneal transplantation of umbilical cord mesenchymal stem cells from Wharton's jelly in the treatment of streptozotocin-induced diabetic rats.沃顿胶源脐带间充质干细胞静脉注射与腹腔注射治疗链脲佐菌素诱导的糖尿病大鼠
Diabetes Res Clin Pract. 2016 Nov;121:102-111. doi: 10.1016/j.diabres.2016.09.008. Epub 2016 Sep 21.
8
Regenerative potential of Wharton's jelly-derived mesenchymal stem cells: A new horizon of stem cell therapy.牙髓基质间充质干细胞的再生潜力:干细胞治疗的新视野。
J Cell Physiol. 2020 Dec;235(12):9230-9240. doi: 10.1002/jcp.29810. Epub 2020 Jun 18.
9
Comparative analysis of human Wharton's jelly mesenchymal stem cells derived from different parts of the same umbilical cord.比较分析同一脐带不同部位来源的人脐带华通氏胶间充质干细胞。
Cell Tissue Res. 2018 Apr;372(1):51-65. doi: 10.1007/s00441-017-2699-4. Epub 2017 Dec 4.
10
Wharton's Jelly Derived-Mesenchymal Stem Cells: Isolation and Characterization.源自华通氏胶的间充质干细胞:分离与鉴定
Acta Med Iran. 2018 Jan;56(1):28-33.

引用本文的文献

1
Tailoring cell therapies for diabetic metabolic phenotypes: a comparative study on the efficacy of various umbilical cord-derived cell regimens.针对糖尿病代谢表型定制细胞疗法:不同脐带源细胞方案疗效的比较研究
Stem Cells Transl Med. 2025 Feb 11;14(2). doi: 10.1093/stcltm/szae083.
2
Deciphering decidual deficiencies in recurrent spontaneous abortion and the therapeutic potential of mesenchymal stem cells at single-cell resolution.解析复发性自然流产中蜕膜缺陷及间充质干细胞的治疗潜力:单细胞分辨率研究。
Stem Cell Res Ther. 2024 Jul 29;15(1):228. doi: 10.1186/s13287-024-03854-6.
3
Differential gene expression of Wharton's jelly-derived mesenchymal cells mediated by graphene oxide in basal and osteo-induced media.
GO 介导的骨髓间充质干细胞在基础和成骨诱导培养基中的差异基因表达。
Mol Biol Rep. 2024 Mar 3;51(1):383. doi: 10.1007/s11033-024-09324-9.
4
Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges.间质干细胞衍生的细胞外囊泡在皮肤伤口愈合中的作用、机遇和挑战。
Mil Med Res. 2023 Aug 17;10(1):36. doi: 10.1186/s40779-023-00472-w.
5
Therapeutic efficacy of umbilical cord-derived stem cells for diabetes mellitus: a meta-analysis study.脐带间充质干细胞治疗糖尿病的疗效:一项荟萃分析研究。
Stem Cell Res Ther. 2020 Nov 16;11(1):484. doi: 10.1186/s13287-020-01996-x.