视神经脊髓炎谱系疾病伴严重体位性低血压，源于下丘脑病变。
Neuromyelitis optica spectrum disorder with severe orthostatic hypotension due to hypothalamic lesions.
机构信息
Department of Neurology, Teikyo University School of Medicine, Kaga 2-11-1, Itabashi-ku, Tokyo 1738605, Japan.
Department of Neurology, Teikyo University School of Medicine, Kaga 2-11-1, Itabashi-ku, Tokyo 1738605, Japan.
出版信息
Mult Scler Relat Disord. 2020 May;40:101977. doi: 10.1016/j.msard.2020.101977. Epub 2020 Jan 31.
BACKGROUND
Rare cases of neuromyelitis optica spectrum disorder (NMOSD) occur with only hypothalamic lesions as the initial lesion, and such cases can present with hypersomnia, endocrinopathy, and autonomic failure. However, orthostatic hypotension (OH) caused by hypothalamic lesions due to NMOSD has not been reported.
CASE REPORT
We report the case of a patient with NMOSD who presented with severe OH due to hypothalamic lesions.
CONCLUSION
We suggest that clinicians should be aware that NMOSD with hypothalamic lesions can present with OH.
背景
极罕见情况下，视神经脊髓炎谱系疾病（NMOSD）仅以下丘脑病变为首发表现，此类病例可出现嗜睡、内分泌异常和自主神经衰竭。然而，NMOSD 所致下丘脑病变引起的直立性低血压（OH）尚未见报道。
病例报告
我们报告了一例 NMOSD 患者，因下丘脑病变出现严重 OH。
结论
我们建议临床医生应注意到，伴有下丘脑病变的 NMOSD 可出现 OH。
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