Sawai Setsu, Mori Masahiro, Makino Takahiro, Nakano Yoshikazu, Kuwabara Satoshi, Kamitsukasa Ikuo
Department of Neurology, Chibaken Saiseikai Narashino Hospital, 1-1-1 Izumi-cho, Narashino City, Chiba 275-8580, Japan.
Department of Neurology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba 260-8670, Japan.
eNeurologicalSci. 2021 Mar 8;23:100335. doi: 10.1016/j.ensci.2021.100335. eCollection 2021 Jun.
Hiccups, nausea and vomiting are known as the clinical manifestations of neuromyelitis optica spectrum disorder (NMOSD) linked to lesions of the area postraema in the medullary tegmentum. Here, we describe a 74-year-old male patient with NMOSD who presented with recurrent syncope due to severe orthostatic hypotension (OH) following symptoms of hiccups, nausea and vomiting. Brain magnetic resonance imaging revealed the lesion of the area postraema and it could be responsible for the symptom of OH. Considering the numerous related reports, we suspect that the prevalence of OH is underreported in the patients with NMOSD. OH may transition into more serious conditions, so it should be evaluated carefully in all patients with NMOSD, particularly when there is a lesion of the area postraema.
呃逆、恶心和呕吐被认为是与延髓被盖后区病变相关的视神经脊髓炎谱系障碍（NMOSD）的临床表现。在此，我们描述了一名74岁的NMOSD男性患者，他在出现呃逆、恶心和呕吐症状后，因严重直立性低血压（OH）反复出现晕厥。脑部磁共振成像显示了后区病变，这可能是OH症状的原因。考虑到众多相关报道，我们怀疑NMOSD患者中OH的患病率被低估了。OH可能会转变为更严重的情况，因此所有NMOSD患者都应仔细评估，尤其是当存在后区病变时。
