Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Izmir, Turkey.
Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Izmir, Turkey.
Diagn Microbiol Infect Dis. 2020 May;97(1):115003. doi: 10.1016/j.diagmicrobio.2020.115003. Epub 2020 Jan 29.
We aimed to evaluate the risk factors of focal involvement in brucellosis.
The data of brucellosis patients were analyzed retrospectively from 2010 through 2019. Patients were divided into two groups: focal involvement (-) and focal involvement (+). The clinical findings, complications and laboratory findings of patients were compared between the two groups.
Two hundred thirty patients were included in the study. One hundred twenty-seven of the patients (55.2%) were male and mean age was 45.8 ± 17.1 (16-86) years. Focal involvement was observed in 98 (42.6%) patients. The variables that differed significantly between groups were age (P < 0.001), fever (P = 0.016), back pain (P < 0.001), leukocyte (P = 0.012), neutrophil (P = 0.004), platelet (P = 0.002), mean platelet volume (MPV) (P = 0.043) and erythrocyte sedimentation rate (ESR) (P = 0.001). Older age (>45 years) and back pain were found to be independent risk factors for predicting focal involvement (P = 0.036 and P < 0.001).
The clinical findings and markers that are significant in determining focal involvement may be useful in identifying complicated brucellosis.
我们旨在评估布鲁氏菌病局灶性受累的危险因素。
回顾性分析 2010 年至 2019 年期间的布鲁氏菌病患者数据。患者分为两组：局灶性受累（-）和局灶性受累（+）。比较两组患者的临床特征、并发症和实验室检查结果。
本研究共纳入 230 例患者，其中 127 例（55.2%）为男性，平均年龄为 45.8±17.1（16-86）岁。98 例（42.6%）患者存在局灶性受累。两组间差异有统计学意义的变量为年龄（P<0.001）、发热（P=0.016）、腰痛（P<0.001）、白细胞（P=0.012）、中性粒细胞（P=0.004）、血小板（P=0.002）、血小板平均体积（MPV）（P=0.043）和红细胞沉降率（ESR）（P=0.001）。年龄>45 岁（P=0.036）和腰痛（P<0.001）是预测局灶性受累的独立危险因素。
在确定局灶性受累方面有意义的临床发现和标志物可能有助于识别复杂的布鲁氏菌病。
