Ríos Antonio, López-Navas Ana I, Carrillo Joaquín, Sánchez Álvaro, Martínez-Alarcón Laura, Ayala-García Marco Antonio, Ramis Guillermo, Parrilla Pascual, Ramírez Pablo
International Collaborative Donor Project ("Proyecto Colaborativo Internacional Donante"), Murcia, Spain; Transplant Unit, Surgery Service, IMIB - Virgen de la Arrixaca University Clinical Hospital, Murcia, Spain; Department of Surgery, University of Murcia, Murcia, Spain.
Department of Psychology, Catholic University of Murcia (UCAM), Murcia, Spain.
Transplant Proc. 2020 Mar;52(2):484-486. doi: 10.1016/j.transproceed.2019.11.046. Epub 2020 Feb 6.
New transplant-related therapies such as xenotransplantation of solid cells, tissues, and organs are still poorly understood, especially in countries without preclinical xenotransplantation programs.
Analyze the attitude toward xenotransplantation among the population of Santiago de Cuba.
Type of study. Cross-sectional observational study.
Random sampling of 455 individuals residing in Santiago de Cuba. Assessment instrument. Validated questionnaire of attitude toward the xenotransplant, "PCID-XenoTx-Ríos." Field work. Random selection based on stratification. Anonymous and self-administered completion.
A total of 49.9% would accept a solid organ xenotransplant if they needed it and the results were similar to those currently obtained with human organs, 27.5% have doubts, and the remaining 22.6% would not accept it. They are presented as statistically significant variables (P < .05): level of studies; comment with the family about the donation; opinion of a partner; religion; opinion of religion; performing prosocial activities; attitude toward donation; previous relationship with the organ donation and transplant; favorable attitude toward live kidney donation. In the multivariate analysis, the following persist: 1. level of university studies: odds ratio (OR) = 5.076; 2. not having a partner: OR = 5.154; 3. belonging to another religion: OR = 2.061; 4. favorable attitude toward organ donation: OR = 5; and 5. favorable attitude toward living donation: OR = 3.759.
The population of Santiago de Cuba is less sensitized toward xenotransplantation, possibly due to ignorance of the issue due to lack of preclinical trials in their countries.
新的移植相关疗法，如实体细胞、组织和器官的异种移植，目前仍未被充分了解，尤其是在没有临床前异种移植项目的国家。
分析古巴圣地亚哥民众对异种移植的态度。
研究类型。横断面观察性研究。
对居住在古巴圣地亚哥的455个人进行随机抽样。评估工具。经过验证的关于对异种移植态度的问卷“PCID-XenoTx-Ríos”。实地工作。基于分层的随机选择。匿名且自行填写。
共有49.9%的人表示如果需要会接受实体器官异种移植，且结果与目前人类器官移植的结果相似；27.5%的人表示怀疑；其余22.6%的人不会接受。呈现出具有统计学意义的变量（P <.05）：学历水平；与家人关于捐赠的讨论；伴侣的意见；宗教信仰；宗教观点；参与亲社会活动；对捐赠的态度；之前与器官捐赠和移植的关系；对活体肾捐赠的积极态度。在多变量分析中，以下因素仍然存在：1. 大学学历水平：比值比（OR）= 5.076；2. 没有伴侣：OR = 5.154；3. 属于其他宗教：OR = 2.061；4. 对器官捐赠的积极态度：OR = 5；5. 对活体捐赠的积极态度：OR = 3.759。
古巴圣地亚哥的民众对异种移植的敏感度较低，可能是由于该国缺乏临床前试验，民众对该问题了解不足。
