具有潜在生物活性的尿嘧啶衍生物的制备及其物理化学性质
Preparation and physicochemical properties of uracil derivatives with potential biological activity.
作者信息
Pecorari P, Vampa G, Albasini A, Rinaldi M, Melegari M, Costi M P
机构信息
Dipartimento di Scienze Farmaceutiche, Università di Modena, Italy.
出版信息
Farmaco Sci. 1988 Apr;43(4):311-8.
PMID:3203736
Abstract
The characterization of mono- and dimethylated 5-substituted uracils was re-examined. Analysis of their physicochemical properties (pKa, U.V., delta 1H-N.M.R.) affords insight into the structural characteristics of 5-substituted uracil alkylated at the ring nitrogens.
摘要
对单甲基化和二甲基化的5-取代尿嘧啶的特性进行了重新研究。对其物理化学性质（pKa、紫外光谱、δ¹H-核磁共振）的分析有助于深入了解在环氮原子处烷基化的5-取代尿嘧啶的结构特征。
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