Department of Diagnostic Radiology, Khoo Teck Puat Hospital, Singapore.
J Med Imaging Radiat Oncol. 2020 Apr;64(2):211-214. doi: 10.1111/1754-9485.13002. Epub 2020 Feb 9.
In the present study, we aimed to assess whether normal saline injection for sealing the biopsy track is useful in reducing the incidence of pneumothorax after computed tomography (CT)-guided percutaneous transthoracic lung biopsy (PTLB).
We retrospectively compared the incidence of pneumothorax in 100 consecutive biopsies (n = 100, group A) that had injection of saline along the track, with historical cohort of same number of consecutive patients who underwent PTLB without injection of saline along the needle track (n = 100, group B). CT-guided biopsies were performed by coaxial technique and 1-3 ml of saline was injected along the tract. Patient chjmirocteristics, lesion size, location and other baseline pjmirometers were compared. Incidence of pneumothorax and number of patients who underwent catheter drainage of pneumothorax was compared in both groups.
Baseline chjmirocteristics were compjmiroble in both groups. Track sealing with saline was successful in all patients. Pneumothorax rate was 46% for patients in group B and 32% in group A (P < 0.05). Seven patients (7%) had insertion of chest drain for pneumothorax in the group B and only 1% in the group A (P < 0.05). No mortality was observed in both groups. No complications were observed in any of the patients due to saline injection.
Track sealing with saline is a simple and safe technique which significantly reduces the incidence of pneumothorax and chest tube insertion after PTLB.
在本研究中，我们旨在评估在 CT 引导经皮经胸肺活检（PTLB）后，使用生理盐水注射封闭活检通道是否有助于降低气胸的发生率。
我们回顾性比较了 100 例连续活检（n=100，A 组）中气胸发生率，这些活检均沿通道注射生理盐水，与历史上相同数量的未沿针道注射生理盐水的连续患者（n=100，B 组）进行比较。CT 引导下活检采用同轴技术，沿通道注射 1-3ml 生理盐水。比较患者特征、病变大小、位置和其他基线参数。比较两组气胸发生率和需要行气胸引流的患者人数。
两组的基线特征具有可比性。所有患者的通道封闭均成功。B 组气胸发生率为 46%，A 组为 32%（P<0.05）。B 组 7 例（7%）患者因气胸行胸腔引流，A 组仅 1%（P<0.05）。两组均无死亡病例。在任何患者中，由于生理盐水注射都没有观察到并发症。
使用生理盐水进行通道封闭是一种简单、安全的技术，可显著降低 PTLB 后气胸的发生率和胸腔引流管的插入率。
