Chung Chaeuk, Kim Yoonjoo, Park Dongil
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungnam National University, Daejeon, Republic of Korea.
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea.
Tuberc Respir Dis (Seoul). 2020 Dec;83(Supple 1):S17-S24. doi: 10.4046/trd.2020.0156. Epub 2020 Dec 4.
Although transthoracic needle biopsy (TTNB) was introduced for lung biopsy about 40 years ago, it is still mainstay of pathologic diagnosis in lung cancer, because it is relatively inexpensive and can obtain tissue regardless of the tumor-bronchus relationship. With several technological advances, proceduralists can perform TTNB more safely and accurately. Utilizing ultrasound-guided biopsy for peripheral lesions in contact with the pleura and rapid onsite evaluation during the procedure are expected to make up the weakness of TTNB. However, due to the inherent limitations of the percutaneous approach, the incidence of complications such as pneumothorax or bleeding is inevitably higher than that of other lung biopsy techniques. Thorough understating of each biopsy modality and additional technique are fundamental for maximizing diagnostic accuracy and minimizing the complications.
尽管经胸针吸活检术（TTNB）约在40年前就被用于肺活检，但它仍是肺癌病理诊断的主要手段，因为它相对便宜，且无论肿瘤与支气管的关系如何都能获取组织。随着多项技术进步，操作医生能够更安全、准确地进行TTNB。利用超声引导对与胸膜接触的周围性病变进行活检以及在操作过程中进行快速现场评估有望弥补TTNB的不足。然而，由于经皮穿刺方法固有的局限性，气胸或出血等并发症的发生率不可避免地高于其他肺活检技术。全面了解每种活检方式及附加技术是实现诊断准确性最大化和并发症最小化的基础。
