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重新评估 24 小时蛋白尿与子痫前期之间的关系,从母婴围产结局方面考虑。

Reappraisal of the relationship between 24-hour proteinuria and preeclampsia in terms of the maternal and perinatal outcomes.

机构信息

Department of Obstetrics and Gynecology, Baskent University Faculty of Medicine, Adana, Turkey.

出版信息

Hypertens Pregnancy. 2020 May;39(2):82-88. doi: 10.1080/10641955.2020.1725038. Epub 2020 Feb 8.

DOI:10.1080/10641955.2020.1725038
PMID:32037908
Abstract

: This study evaluated the association between proteinuria levels and maternal, and perinatal outcomes of preeclampsia patients and determined the cutoff values for predicting severe complications.: We retrospectively evaluated the records of 412 patients with proteinuric preeclampsia.: Median proteinuria levels were significantly higher in patients with severe maternal and adverse perinatal outcomes than in those without such outcomes, except in cases of placental abruption and late preterm delivery.: Proteinuria levels may aid in diagnosing preeclampsia and indicating early intervention. The revised guidelines do not suggest that proteinuria encountered during pregnancy is clinically insignificant.

摘要

本研究评估了蛋白尿水平与子痫前期患者的母婴和围产结局之间的关联,并确定了预测严重并发症的截断值。

我们回顾性评估了 412 例蛋白尿性子痫前期患者的记录。

中位数蛋白尿水平在有严重母亲和不良围产结局的患者中显著高于无此类结局的患者,除胎盘早剥和晚期早产外。

蛋白尿水平可能有助于诊断子痫前期并提示早期干预。修订后的指南并不表明妊娠期间发现的蛋白尿在临床上无意义。

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引用本文的文献

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Association between hypoproteinaemia with massive proteinuria and small for gestational age in pre-eclampsia: a single-centre, retrospective cohort study using propensity score matching.子痫前期中低蛋白血症伴大量蛋白尿与胎儿生长受限的相关性:一项采用倾向评分匹配的单中心回顾性队列研究。
BMJ Open. 2023 Jul 18;13(7):e071835. doi: 10.1136/bmjopen-2023-071835.
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Association between proteinuria and placental pathology in preeclampsia: A retrospective study.子痫前期蛋白尿与胎盘病理学之间的关联:一项回顾性研究。
SAGE Open Med. 2021 Nov 23;9:20503121211058053. doi: 10.1177/20503121211058053. eCollection 2021.