Artificial Organ Technology Laboratory, Biomanufacturing Centre, School of Mechanical and Electrical Engineering, Soochow University, Suzhou, China.
Brunel Institute for Bioengineering, Brunel University London, Uxbridge, UK.
Int J Artif Organs. 2020 Sep;43(9):559-569. doi: 10.1177/0391398820902470. Epub 2020 Feb 10.
It has been reported that long-term use of continuous-flow mechanical circulatory support devices (CF-MCSDs) may induce complications associated with diminished pulsatility. Pulsatile-flow mechanical circulatory support devices (PF-MCSDs) have the potential of overcoming these shortcomings with the advance of technology. In order to promote in-depth understanding of PF-MCSD technology and thus encourage future mechanical circulatory support device innovations, engineering perspectives of PF-MCSD systems, including mechanical designs, drive mechanisms, working principles, and implantation strategies, are reviewed in this article. Some emerging designs of PF-MCSDs are introduced, and possible elements for next-generation PF-MCSDs are identified.
据报道，长期使用连续血流机械循环支持设备（CF-MCSD）可能会引起与搏动减弱相关的并发症。脉动血流机械循环支持设备（PF-MCSD）随着技术的进步有可能克服这些缺点。为了促进对 PF-MCSD 技术的深入了解，从而鼓励未来的机械循环支持设备创新，本文综述了 PF-MCSD 系统的工程视角，包括机械设计、驱动机制、工作原理和植入策略。介绍了一些新兴的 PF-MCSD 设计，并确定了下一代 PF-MCSD 的可能要素。
