Appavu Brian, Burrows Brian T, Foldes Stephen, Adelson P David
Barrow Neurological Institute, Phoenix Children's Hospital, Phoenix, AZ, United States.
Department of Child Health, University of Arizona College of Medicine - Phoenix, Phoenix, AZ, United States.
Front Neurol. 2019 Nov 26;10:1261. doi: 10.3389/fneur.2019.01261. eCollection 2019.
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in children. Improved methods of monitoring real-time cerebral physiology are needed to better understand when secondary brain injury develops and what treatment strategies may alleviate or prevent such injury. In this review, we discuss emerging technologies that exist to better understand intracranial pressure (ICP), cerebral blood flow, metabolism, oxygenation and electrical activity. We also discuss approaches to integrating these data as part of a multimodality monitoring strategy to improve patient care.
创伤性脑损伤（TBI）是儿童发病和死亡的主要原因。需要改进实时脑生理监测方法，以更好地了解继发性脑损伤何时发生，以及哪些治疗策略可以减轻或预防此类损伤。在本综述中，我们讨论了现有的新兴技术，以更好地了解颅内压（ICP）、脑血流量、代谢、氧合和电活动。我们还讨论了将这些数据整合为多模态监测策略一部分以改善患者护理的方法。
