Foshee James P, Trofymenko Oleksandr, Zeitouni Nathalie C
Dr. Foshee is with the Division of Dermatology, University of Arizona College of Medicine in Tucson, Arizona.
Dr. Trofymenko is with the University of Arizona College of Medicine in Tucson, Arizona.
J Clin Aesthet Dermatol. 2019 Dec;12(12):39-43. Epub 2019 Dec 1.
Dermatofibrosarcoma protuberans (DFSP) is a locally aggressive tumor, uncommonly occurring on the head and neck where these deeply infiltrating tumors might violate underlying neurovascular structures. Treatment is typically surgical, whether by Mohs micrographic surgery (MMS) or wide local excision (WLE). However, there is a paucity of literature describing functional neurologic outcomes following surgical extirpation of facial DFSP. Thus, we sought to examine the functional neurologic outcomes in patients undergoing either MMS or WLE for facial DFSP. Two patients with DFSP involving facial nerve danger zones treated by the multidisciplinary team with MMS and subsequent reconstruction were studied. Additionally, a comprehensive literature review of facial DFSP with regard to neurologic functional status was performed. From our research, only 10 of 46 patients with facial DFSP had neurologic functional status reported, with four of these cases having notable facial nerve deficits. Of our cases, both patients experienced transient neurologic deficits and neither had evidence of recurrence. The proper assessment and reporting of postoperative functional recovery should be undertaken following facial DFSP resection and consideration should be given to a multidisciplinary treatment approach.
隆突性皮肤纤维肉瘤(DFSP)是一种局部侵袭性肿瘤,很少发生于头颈部,而这些深部浸润性肿瘤可能侵犯潜在的神经血管结构。治疗通常采用手术,无论是莫氏显微外科手术(MMS)还是广泛局部切除(WLE)。然而,关于面部DFSP手术切除后的功能神经学结果的文献较少。因此,我们试图研究接受MMS或WLE治疗面部DFSP患者的功能神经学结果。研究了2例累及面神经危险区的DFSP患者,由多学科团队采用MMS治疗并随后进行重建。此外,还对面部DFSP的神经功能状态进行了全面的文献综述。根据我们的研究,46例面部DFSP患者中只有10例报告了神经功能状态,其中4例有明显的面神经缺损。在我们的病例中,两名患者均出现短暂的神经功能缺损,且均无复发迹象。面部DFSP切除术后应进行术后功能恢复的正确评估和报告,并应考虑采用多学科治疗方法。