Department of Gynecologic Oncology, The First Affiliated Hospital of Zhengzhou University, Jianshe East Road, Zhengzhou 450052, PR China.
Department of Obstetrics & Gynecology, Henan Province People's Hospital, 7 Weiwu Road, Zhengzhou 450052, PR China.
Future Oncol. 2020 Mar;16(8):307-316. doi: 10.2217/fon-2019-0732. Epub 2020 Feb 10.
To reveal the prognostic significance of serum albumin (ALB) concentration in endometrial cancer (EC) patients in China. 345 EC patients were enrolled in a single center, and the preoperative serum ALB concentration were measured. Kaplan-Meier curve analysis and Cox proportional hazards regression model were performed to evaluate the associations between ALB concentration and overall survival (OS) of EC patients. The EC patients with lower preoperative serum ALB concentration exhibited a significantly poorer OS (p < 0.05). Univariate analysis and multivariate analysis indicated that serum ALB concentration was an independent prognostic factor of unfavorable OS for EC patients. Our results showing that ALB concentration may serve as an independent prognostic factor for EC patients.
为了揭示血清白蛋白（ALB）浓度在中国子宫内膜癌（EC）患者中的预后意义。在单中心纳入 345 例 EC 患者，并检测其术前血清 ALB 浓度。采用 Kaplan-Meier 曲线分析和 Cox 比例风险回归模型评估 ALB 浓度与 EC 患者总生存（OS）之间的关系。术前血清 ALB 浓度较低的 EC 患者的 OS 明显较差（p < 0.05）。单因素分析和多因素分析表明，血清 ALB 浓度是 EC 患者不良 OS 的独立预后因素。我们的研究结果表明，ALB 浓度可能是 EC 患者的一个独立预后因素。
