Dostál M, Vasků J, Bílková B, Cerný J, Vasků J, Sotolová O, Vasků A, Urbánek P, Gregor Z, Guba P
Institute of Pathological Physiology, Faculty of Medicine, J.E. Purkynĕ University, Brno, Czechoslovakia.
Int J Artif Organs. 1988 Nov;11(6):475-81.
A group of 10 experimental calves that lived for 61-147 days with a TAH was used to study serum aldosterone levels by RIA with ALDOCTK-125 CEA Kit (Sorin Biomedica, Italy). The aldosterone levels were plotted against the serum sodium and potassium, body weight, CVP, urinary sodium and potassium and with hematocrit levels. In these experiments, three types of TAH (TNS-BRNO II, VII, and Rostock) were used. The levels of aldosterone were already high before the surgery and during the entire pumping period, which indicates the development of secondary aldosteronism. The study deals with the mechanisms that participate in the development of aldosteronism in each phase of the experiment with the TAH.
一组10头接受全人工心脏（TAH）并存活61至147天的实验小牛，用于使用ALDOCTK - 125 CEA试剂盒（意大利索林生物医学公司）通过放射免疫分析法研究血清醛固酮水平。将醛固酮水平与血清钠和钾、体重、中心静脉压、尿钠和钾以及血细胞比容水平进行绘图分析。在这些实验中，使用了三种类型的全人工心脏（TNS - BRNO II、VII和罗斯托克型）。醛固酮水平在手术前和整个泵血期间就已经很高，这表明继发性醛固酮增多症的发展。该研究探讨了在全人工心脏实验的每个阶段中参与醛固酮增多症发展的机制。
