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上肢神经缺损修复的循证方法:文献综述与当前手术管理算法

Evidence-Based Approach to Nerve Gap Repair in the Upper Extremity: A Review of the Literature and Current Algorithm for Surgical Management.

作者信息

Huayllani Maria T, Boczar Daniel, Forte Antonio J, Rinker Brian

机构信息

From the Division of Plastic Surgery and Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Jacksonville, FL.

出版信息

Ann Plast Surg. 2020 Jun;84(6S Suppl 5):S369-S374. doi: 10.1097/SAP.0000000000002278.

DOI:10.1097/SAP.0000000000002278
PMID:32039999
Abstract

The upper extremity is the most common site for nerve injuries. In most cases, direct repair can be performed, but when a critical gap occurs, special techniques must be used to enhance nerve regeneration and allow recovery of sensory and motor functions. These techniques include the use of autografts, processed nerve allografts, and conduits. However, surprisingly few studies have compared outcomes from the different methods of nerve gap repair in a rigorous fashion. There is a lack of evidence-based guidelines for the management of digital and motor and mixed nerve injuries with a nerve gap. The purpose of this study is to perform a comprehensive literature review and propose a rational algorithm for management of nerve injuries with a critical gap.

摘要

上肢是神经损伤最常见的部位。在大多数情况下,可以进行直接修复,但当出现关键间隙时,必须采用特殊技术来促进神经再生并恢复感觉和运动功能。这些技术包括使用自体移植物、处理过的同种异体神经移植物和导管。然而,令人惊讶的是,很少有研究以严谨的方式比较不同神经间隙修复方法的结果。对于伴有神经间隙的指神经、运动神经和混合神经损伤的处理,缺乏基于证据的指南。本研究的目的是进行全面的文献综述,并提出一种合理的算法来处理伴有关键间隙的神经损伤。

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Evidence-Based Approach to Nerve Gap Repair in the Upper Extremity: A Review of the Literature and Current Algorithm for Surgical Management.上肢神经缺损修复的循证方法:文献综述与当前手术管理算法
Ann Plast Surg. 2020 Jun;84(6S Suppl 5):S369-S374. doi: 10.1097/SAP.0000000000002278.
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Autograft Substitutes: Conduits and Processed Nerve Allografts.自体移植替代物:导管与处理过的同种异体神经移植物。
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引用本文的文献

1
Updates in peripheral nerve surgery of the upper extremity: diagnosis and treatment options.上肢周围神经外科的进展:诊断与治疗选择
Ann Transl Med. 2023 Oct 25;11(11):391. doi: 10.21037/atm-23-1500. Epub 2023 Sep 18.
2
Principles of microvascular surgery in the upper extremity.上肢微血管外科手术原则。
Eur J Orthop Surg Traumatol. 2024 Oct;34(7):3647-3659. doi: 10.1007/s00590-023-03749-x. Epub 2023 Oct 24.
3
Bioactive Nanofiber-Based Conduits in a Peripheral Nerve Gap Management-An Animal Model Study.基于生物活性纳米纤维的周围神经间隙管理导管:一项动物模型研究。
Int J Mol Sci. 2021 May 25;22(11):5588. doi: 10.3390/ijms22115588.