Division of Hand Surgery, Department of Orthopedic Surgery, Virginia Commonwealth University Health System, 1200 East Broad Street, Richmond, VA, USA.
Division of Hand Surgery, Department of Orthopedic Surgery, Virginia Commonwealth University Health System, 1200 East Broad Street, Richmond, VA, USA.
Hand Clin. 2024 Aug;40(3):357-367. doi: 10.1016/j.hcl.2024.04.005. Epub 2024 Jun 4.
Processed nerve allograft is a widely accepted tool for reconstructing peripheral nerve defects. Repair parameters that need to be considered include gap length, nerve diameter, nerve type (motor, sensory, or mixed), and the soft tissue envelope. Although the use of processed nerve allograft must be considered based on each unique clinical scenario, a rough algorithm can be formed based on the available animal and clinical literature. This article critically reviews the current surgical algorithm, defines the role of processed nerve allograft compared with nerve autograft, and discusses how this role may change in the future.
神经移植物是一种广泛接受的修复外周神经缺损的工具。需要考虑的修复参数包括间隙长度、神经直径、神经类型（运动、感觉或混合）和软组织鞘。尽管神经移植物的使用必须根据每个独特的临床情况来考虑，但可以根据现有的动物和临床文献制定一个大致的算法。本文批判性地回顾了目前的手术算法，定义了神经移植物与神经自体移植物的作用，并讨论了这种作用在未来可能会如何变化。
