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是否有足够的证据支持在女性下尿路功能障碍中使用激光和其他热疗?ICI-RS 2019 报告。

Is there enough evidence to justify the use of laser and other thermal therapies in female lower urinary tract dysfunction? Report from the ICI-RS 2019.

机构信息

Department of Urogynaecology, Kings College Hospital, London, UK.

Kings College Hospital, London, UK.

出版信息

Neurourol Urodyn. 2020 Jul;39 Suppl 3:S140-S147. doi: 10.1002/nau.24298. Epub 2020 Feb 10.

DOI:10.1002/nau.24298
PMID:32040871
Abstract

AIMS

There is increasing evidence to suggest that thermomodulation may have a role in the management of women with lower urinary tract dysfunction (LUTD) and there has been widespread adoption of laser and radiofrequency (RF) therapies within clinical practice. However, in many areas of LUTD, the data are still limited and there remains a need for further evaluation of the safety and efficacy of thermal therapy. The aim of this study proposal is to report the findings of the International Consultation on Incontinence Research Society to clarify our current knowledge regarding the evidence for thermal therapy in LUTD and to set research priorities for the future.

METHODS

Literature review based on the search terms: "laser," "radiofrequency," "genitourinary syndrome of the menopause" or "urogenital atrophy," "stress urinary incontinence (SUI)," "pelvic organ prolapse," "OAB" or "overactive bladder," and "urinary tract infection."

RESULTS

The current available evidence, though of low or very low quality, appears promising for the use of laser therapy in the management of genitourinary syndrome of the menopause, there are some data to suggest a possible role in SUI although very little evidence for urogenital prolapse. At present, the evidence supporting the use of laser in OAB and recurrent urinary tract infection is limited or lacking, while the available evidence for RF in the management of all forms of LUTD is much less robust.

CONCLUSIONS

Laser and RF are being introduced clinically as a minimally invasive, low-risk interventions for women with LUTD although at present, the evidence supporting usage is limited. Consequently, there is an urgent need to demonstrate the safety and efficacy with prospective long-term studies including sham studies and comparative studies with current standard therapy.

摘要

目的

越来越多的证据表明,热调节可能在管理下尿路功能障碍(LUTD)女性方面发挥作用,激光和射频(RF)疗法已在临床实践中广泛应用。然而,在 LUTD 的许多领域,数据仍然有限,仍然需要进一步评估热疗的安全性和疗效。本研究方案旨在报告国际尿控协会咨询会议的研究结果,以阐明我们目前对 LUTD 中热疗证据的了解,并为未来确定研究重点。

方法

根据搜索词“激光”、“射频”、“绝经后女性泌尿生殖系统综合征”或“泌尿生殖萎缩”、“压力性尿失禁(SUI)”、“盆腔器官脱垂”、“OAB”或“膀胱过度活动症”和“尿路感染”进行文献回顾。

结果

目前的可用证据质量较低或非常低,但似乎有希望将激光疗法用于治疗绝经后女性泌尿生殖系统综合征,有一些数据表明其在 SUI 方面可能具有作用,但在泌尿生殖系统脱垂方面的证据很少。目前,支持激光治疗 OAB 和复发性尿路感染的证据有限或缺乏,而支持 RF 治疗所有类型 LUTD 的证据则少得多。

结论

激光和 RF 作为一种微创、低风险的干预措施,正在临床中引入,用于治疗 LUTD 女性,尽管目前支持使用的证据有限。因此,迫切需要通过前瞻性长期研究,包括假手术研究和与当前标准治疗的比较研究,证明其安全性和疗效。

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