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急性胰腺炎的巴尔萨泽评分与中性粒细胞-淋巴细胞比值

Balthazar Score and Neutrophil-Lymphocytes Ratio in Acute Pancreatitis.

作者信息

Petrescu G S, Georgescu I, Petrescu A M, Rădulescu D, Petrescu M O, Pătrașcu Ș

机构信息

PhD student, University of Medicine and Pharmacy of Craiova, Romania.

Department I of Surgery, University of Medicine and Pharmacy of Craiova, Romania.

出版信息

Curr Health Sci J. 2019 Jul-Sep;45(3):316-320. doi: 10.12865/CHSJ.45.03.11. Epub 2019 Sep 30.

Abstract

Acute pancreatitis is a pathological entity that poses numerous diagnostic and treatment problems. Severe form is a real challenge for a physician because it has multiple obscure causes, as well as a complex pathophysiology. Thus, the diagnosis is difficult and the choice of the right time for surgical treatment is controversial, the treatment being more frequently nonspecific, supportive for the various affected systems and organs. On a group of 337 patients, laboratory and imaging investigations were performed to diagnose and determine the severity score of acute pancreatitis and the correlation level between the neutrophil-lymphocytes ratio values and the Balthazar score, as a valid assessment method for local and systemic inflammatory changes. The distribution's study of acute pancreatitis by gender according to etiology confirms the predominance of the acute ethanolic pancreatitis in male, but also the higher proportion (54%) of male pancreatitis (181 man vs. 156 women) with gender ratio male/female 1.16/1. The neutrophil-lymphocytes ratio mean value varied according with the Balthazar severity score, that got higher as acute pancreatitis got more advanced and with a certain cut-off value can be considered a simple indicator to determine the severity of acute pancreatitis.

摘要

急性胰腺炎是一种存在诸多诊断和治疗难题的病理实体。重症急性胰腺炎对医生而言是一项严峻挑战,因为其病因众多且隐匿,病理生理过程复杂。因此,诊断困难,手术治疗时机的选择存在争议,治疗方式往往较为非特异性,主要是对各个受累系统和器官进行支持治疗。对337例患者进行了实验室和影像学检查,以诊断并确定急性胰腺炎的严重程度评分,以及中性粒细胞与淋巴细胞比值和巴尔萨泽(Balthazar)评分之间的关联程度,后者是评估局部和全身炎症变化的有效方法。根据病因对急性胰腺炎进行的性别分布研究证实,酒精性急性胰腺炎在男性中占主导地位,但男性胰腺炎患者的比例(54%,181例男性对156例女性)也更高,男女比例为1.16/1。中性粒细胞与淋巴细胞比值的平均值随巴尔萨泽严重程度评分而变化,随着急性胰腺炎病情进展该比值升高,且在达到一定临界值时可被视为判断急性胰腺炎严重程度的一个简单指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af35/6993759/8f887778e3d0/CHSJ-45-3-316-fig1.jpg

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