Kiyak Mevlut, Tanoglu Alpaslan
Department of Gastroenterology, Health Science University, Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital, Istanbul, Turkey.
Curr Health Sci J. 2022 Jan-Mar;48(1):81-87. doi: 10.12865/CHSJ.48.01.12. Epub 2022 Mar 31.
Acute pancreatitis (AP) clinic has a wide spectrum ranging from asymptomatic cases to mortality. Early diagnosis and prediction are of great importance to prevent mortality in AP patients. Many prognostic scoring systems have been developed for AP to date. At the time of the initial assessment of attendance to the emergency department (ED), it is impractical to use existing prognostic scoring systems for patients with a diagnosis of AP in most patients. The prognostic performances of radiological and clinical scoring systems of 329 patients diagnosed with acute pancreatitis were compared in terms of C-reactive protein-albumin ratio (CAR) levels, mortality and severity according to Balthazar score. It was observed that the CAR value increased as the AP severity increased. For mortality estimation, the ROC curve was used for sensitivity, specificity, and cut-off values for each scoring system for CAR. When mild pancreatitis and severe pancreatitis were compared according to Balthazar score, the differences between CAR were statistically significant and positive correlations were present. The CAR value has been shown to be a useful clinical tool that can be used with its high predictive value. CAR has the advantages of being easily accessible, inexpensive, and having moderately high diagnostic power to predict AP severity.
急性胰腺炎（AP）的临床表现范围广泛，从无症状病例到死亡。早期诊断和预测对于预防AP患者的死亡至关重要。迄今为止，已经开发了许多用于AP的预后评分系统。在急诊科（ED）进行初次评估时，对于大多数诊断为AP的患者来说，使用现有的预后评分系统是不切实际的。根据巴尔萨泽评分，比较了329例诊断为急性胰腺炎患者的放射学和临床评分系统在C反应蛋白-白蛋白比值（CAR）水平、死亡率和严重程度方面的预后表现。观察到随着AP严重程度的增加，CAR值升高。对于死亡率估计，使用ROC曲线来确定每个CAR评分系统的敏感性、特异性和临界值。根据巴尔萨泽评分比较轻度胰腺炎和重度胰腺炎时，CAR之间的差异具有统计学意义且呈正相关。CAR值已被证明是一种有用的临床工具，具有较高的预测价值。CAR具有易于获取、成本低廉以及对预测AP严重程度具有中等较高诊断能力的优点。
