Kayalı Dinç Ayşe Seçil, Çayönü Melih, Boynueğri Süleyman, Ünsal Tuna Evrim, Eryılmaz Adil
Otolaryngology, Ankara Bilkent City Hospital, Ankara, TUR.
Cureus. 2020 Jan 4;12(1):e6560. doi: 10.7759/cureus.6560.
The aim of this study was to evaluate the efficacy of salvage hyperbaric oxygen therapy (HBOT) for sudden sensorineural hearing loss (SSNHL); HBOT is performed after three weeks of the onset of the disease.
This retrospective clinical study included patients with unilateral idiopathic SSNHL. All patients admitted to the hospital with the diagnosis of SSNHL were given standard steroid treatment within the 14 days of the onset of the SSNHL. We compared the two study groups - Group A: patients receiving steroid treatment within the first 14 days; Group B: patients receiving corticosteroid treatment within the first 14 days, but unresponsive to this treatment, and began to receive HBOT after three weeks of the onset of SSNHL for the purpose of salvage therapy.
A total of 50 patients were included in the study. The mean age of the patients was 50.6 ± 14.1 years. There was not a significant difference in the degree of hearing loss between the groups based on the findings from audiometric examinations performed at the time of diagnosis. It was observed that salvage HBOT was not effective when the initial and post-treatment audiometric tests were compared.
According to our results, salvage HBOT was not efficient when performed three weeks after the onset of the SSNHL for patients who did not respond to corticosteroid treatment.
本研究旨在评估挽救性高压氧治疗(HBOT)对突发性感音神经性听力损失(SSNHL)的疗效;HBOT在疾病发作三周后进行。
这项回顾性临床研究纳入了单侧特发性SSNHL患者。所有因SSNHL诊断入院的患者在SSNHL发作的14天内均接受了标准的类固醇治疗。我们比较了两个研究组——A组:在最初14天内接受类固醇治疗的患者;B组:在最初14天内接受皮质类固醇治疗但对此治疗无反应,并在SSNHL发作三周后开始接受HBOT以进行挽救治疗的患者。
本研究共纳入50例患者。患者的平均年龄为50.6±14.1岁。根据诊断时进行的听力测试结果,两组之间的听力损失程度没有显著差异。当比较初始和治疗后的听力测试时,发现挽救性HBOT无效。
根据我们的结果,对于对皮质类固醇治疗无反应的患者,在SSNHL发作三周后进行挽救性HBOT是无效的。