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多节段腰椎后路椎间融合术治疗退行性脊柱侧凸的临床及影像学结果:一项至少随访2年的连续病例系列研究

The clinical and radiological outcomes of multilevel posterior lumbar interbody fusion in the treatment of degenerative scoliosis: a consecutive case series with minimum 2 years follow up.

作者信息

Sabou Silviu, Carrasco Roberto, Verma Rajat, Siddique Irfan, Mohammad Saeed

机构信息

Department of Complex Spinal Surgery, Salford Royal Hospital NHS Foundation Trust, Stott Lane, Lancashire, UK.

Division of Population Health, Health Services Research & Primary Care, Manchester, UK.

出版信息

J Spine Surg. 2019 Dec;5(4):520-528. doi: 10.21037/jss.2019.12.02.

Abstract

BACKGROUND

Surgical treatment for adult degenerative scoliosis (ADS) is a complex undertaking and is associated with a high complication rate. Our aim was to evaluate the clinical and radiological outcomes, mortality and morbidity of multilevel posterior lumbar interbody fusion (MPLIF) in the treatment in ADS based on the experience of a single tertiary referral center for spinal surgery.

METHODS

We performed a retrospective analysis of prospectively collected data of consecutive patients who had undergone multi-level posterior interbody fusion for degenerative scoliosis. We prospectively recorded patients' demographics, co-morbidities; coronal and sagittal plane deformity assessment and surgical details: number of instrumented levels, and intra-operative and postoperative complications. Functional outcomes and patient-reported complications were entered in our local spine surgery database (part of the Eurospine Spine Tango Registry) and used to collect data on functional scores and patient-reported complications preoperatively and at 6, 12 and 24 months' follow-up.

RESULTS

Our study involved 13 males and 51 females with a mean age of 70.26 (range 49-90, SD 8.9). MPLIF was performed at five levels in one patient, four levels in 29 patients, three levels in 20 patients, and two levels in 14 patients. There were a total of 14 (21.87%) major, minor and mechanical complications. There were no procedure-related mortalities. The average COMI and Eq5d scores improved significantly post-surgery, and this improvement was maintained at a mean follow-up of up to two years.

CONCLUSIONS

Multilevel posterior interbody fusion is a safe procedure, and in selected cases can result in good clinical and radiological outcomes with improvement in patient quality of life.

摘要

背景

成人退变性脊柱侧凸(ADS)的手术治疗是一项复杂的工作,且并发症发生率很高。我们的目的是基于一家单一的脊柱外科三级转诊中心的经验,评估多节段腰椎后路椎间融合术(MPLIF)治疗ADS的临床和影像学结果、死亡率及发病率。

方法

我们对前瞻性收集的连续接受退变性脊柱侧凸多节段后路椎间融合术患者的数据进行了回顾性分析。我们前瞻性记录了患者的人口统计学资料、合并症;冠状面和矢状面畸形评估以及手术细节:内固定节段数、术中及术后并发症。功能结果和患者报告的并发症被录入我们当地的脊柱外科数据库(欧洲脊柱协会脊柱探戈注册中心的一部分),并用于收集术前以及术后6个月、12个月和24个月随访时的功能评分和患者报告并发症的数据。

结果

我们的研究纳入了13名男性和51名女性,平均年龄为70.26岁(范围49 - 90岁,标准差8.9)。1例患者进行了5节段的MPLIF,29例患者进行了4节段,20例患者进行了3节段,14例患者进行了2节段。总共有14例(21.87%)出现了严重、轻微及机械性并发症。没有与手术相关的死亡病例。术后平均COMI和Eq5d评分显著改善,且这种改善在平均长达两年的随访中得以维持。

结论

多节段腰椎后路椎间融合术是一种安全的手术方法,在特定病例中可产生良好的临床和影像学结果,并改善患者生活质量。

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