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脱矿骨纤维(DBF)与超临界二氧化碳(SCCO)处理的同种异体骨在腰椎前路椎间融合术(ALIF)中的联合应用。

The use of demineralised bone fibres (DBF) in conjunction with supercritical carbon dioxide (SCCO) treated allograft in anterior lumbar interbody fusion (ALIF).

作者信息

Rajadurai Jeremy, Lovric Vedran, Mobbs Ralph J, Choy Wen Jie, Walsh William R

机构信息

NeuroSpine Surgery Research Group (NSURG), Sydney, Australia.

Prince of Wales Private Hospital, Randwick, NSW, Australia.

出版信息

J Spine Surg. 2019 Dec;5(4):589-595. doi: 10.21037/jss.2019.10.04.

Abstract

Spinal fusion is a common procedure for the treatment of various spinal pathologies. Since the early days, spinal fusion has been carried out with the use of bone grafts as interbody spacers. With the development of synthetic interbody implants, bone grafts were used to facilitate fusion. Although autograft provides the best outcomes for fusion, allografts have been sought after due to donor site morbidity and other shortcomings. Currently, a vast variety of demineralised bone matrix (DBM) products are available with their methods of processing and preparation impacting their properties and clinical outcomes. Demineralised bone fibres (DBF), a form a DBM can be easily packed into implants when mixed with other substances such as allograft bone and patient's blood providing a scaffold for the mixture. We report two cases of anterior lumbar interbody fusion (ALIF) utilising a titanium-polyetheretherketone (PEEK) interbody cage filled with DBF, allograft and patient's blood with a maximum of 12 months follow-up outcome.

摘要

脊柱融合术是治疗各种脊柱疾病的常见手术。从早期开始,脊柱融合术就使用骨移植作为椎间融合器。随着合成椎间植入物的发展,骨移植被用于促进融合。尽管自体骨移植为融合提供了最佳效果,但由于供体部位的并发症和其他缺点,同种异体骨移植一直备受青睐。目前,有各种各样的脱矿骨基质(DBM)产品,其加工和制备方法会影响其性能和临床效果。脱矿骨纤维(DBF)是DBM的一种形式,当与同种异体骨和患者血液等其他物质混合时,它可以很容易地填充到植入物中,为混合物提供支架。我们报告了两例使用填充有DBF、同种异体骨和患者血液的钛-聚醚醚酮(PEEK)椎间融合器进行前路腰椎椎间融合术(ALIF)的病例,并给出了最长12个月的随访结果。

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