Division Medizinische Mikrobiologie, Paracelsus Medizinische Privatuniversität Salzburg, Universitätsinstitut für Medizinisch-Chemische Labordiagnostik, Salzburg, Austria.
General Practioner, Salzburg, Austria.
Am J Trop Med Hyg. 2020 Apr;102(4):844-846. doi: 10.4269/ajtmh.19-0744.
We report the case of a 56-year-old woman with microfilaremic dirofilariasis due to , which is a very rare condition in humans. Of note, just one of six large-volume blood samples of this patient was positive for microfilariae. Polymerase chain reaction (PCR) and sequencing of the parasite gene determined the geographic origin of the causative helminth. The patient was treated successfully with doxycycline. This drug was chosen because of the patient's reluctance to the use of ivermectin and to provide an anthelmintic effect by targeting the bacterial endosymbiont present in most filarial species.
我们报告了一例 56 岁女性因感染导致微丝蚴血症性盘尾丝虫病的病例，这种情况在人类中非常罕见。值得注意的是，该患者的 6 大体积血样中只有 1 份为微丝蚴阳性。寄生虫基因的聚合酶链反应（PCR）和测序确定了致病蠕虫的地理起源。该患者成功接受了多西环素治疗。选择这种药物是因为患者不愿意使用伊维菌素，并通过针对大多数丝虫物种中存在的细菌内共生体来提供驱虫作用。
