Neurology Department, Wellington Hospital, Wellington, New Zealand.
General Medicine Department, Hutt Hospital, Lower Hutt, New Zealand.
Intern Med J. 2021 Mar;51(3):385-389. doi: 10.1111/imj.14782.
Patients with Parkinsonism are 1.5 times more likely than comparators to be hospitalised and have a significantly longer length of stay in hospital. Medication delays, inappropriate medication omission, and administration of contraindicated medications likely contribute to these poor outcomes. Education and hospital system interventions may reduce these errors.
To determine the effectiveness of a multimodal education and awareness campaign in reducing medication errors in patients with Parkinsonism at Hutt Hospital.
We performed an audit of hospital medication charts to establish the baseline medication error rate and patient outcomes over a 3-month period. We then delivered an intervention consisting of staff education sessions, a sticker alert system and increased priority for pharmacist review of patient drug charts. We repeated the audit after the intervention.
In the initial audit, the medication error rate was 22.5%, the clinical complication rate was 45% and one death was directly attributable to medication error. At follow up, the medication error and complication rates were 9.3% (absolute difference 13% (95% conflict of interest (CI) 10-16.4), P < 0.001) and 38% (absolute difference 7% (95% CI -19 to 34), P = 0.59), respectively, and there were no attributable deaths. The average length of stay before and after the intervention was 13 and 8 days respectively (absolute difference 5.7 days (95% CI -1.8 to 13.3), P = 0.135).
There was a high in-hospital medication error rate for Parkinsonian patients. The intervention resulted in a statistically significantly improvement in the medication error rate. The estimated reductions in complication rate and length of stay may be clinically important. Similar interventions may be beneficial in other institutions.
帕金森病患者住院的可能性比对照组高 1.5 倍,住院时间明显更长。药物延迟、不适当的药物停用以及禁忌药物的使用可能导致这些不良结果。教育和医院系统干预可能会减少这些错误。
确定多模式教育和意识运动在减少哈特医院帕金森病患者药物错误方面的有效性。
我们对医院的药物图表进行了审核,以确定 3 个月期间的药物错误率和患者结局的基线。然后,我们实施了一项干预措施,包括员工教育课程、贴纸警示系统以及增加药剂师审查患者药物图表的优先级。干预后,我们再次进行了审核。
在最初的审核中,药物错误率为 22.5%,临床并发症率为 45%,有 1 例死亡直接归因于药物错误。在随访时,药物错误和并发症的发生率分别为 9.3%(绝对差异 13%(95%置信区间 10-16.4),P<0.001)和 38%(绝对差异 7%(95%置信区间 -19 至 34),P=0.59),且无归因于死亡。干预前后的平均住院时间分别为 13 天和 8 天(绝对差异 5.7 天(95%置信区间 -1.8 至 13.3),P=0.135)。
帕金森病患者的院内药物错误率很高。干预措施使药物错误率显著降低。并发症发生率和住院时间的估计减少可能具有临床意义。类似的干预措施可能对其他机构有益。