Division of Child and Adolescent Psychiatry, Department of Psychiatry, Zucker Hillside Hospital, Glen Oaks, New York, USA.
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
J Child Adolesc Psychopharmacol. 2020 May;30(4):244-249. doi: 10.1089/cap.2019.0149. Epub 2020 Feb 11.
Research has shown that dialectical behavior therapy (DBT) is an effective treatment modality to decrease suicidal ideation, incidents of nonsuicidal self-injurious behavior, and suicide attempts in an adolescent outpatient population. However, research on the impact of DBT on depressive and manic symptoms for adolescents and within an inpatient setting is limited. The purpose of this study is to examine whether DBT significantly decreases depressive and manic symptoms compared with treatment as usual (TAU) for inpatient adolescents. We conducted a retrospective chart review for adolescents receiving inpatient DBT and for a historical control group on the same unit before DBT (i.e., TAU). Group differences for continuous outcomes were analyzed using analysis of covariance (ANCOVA), where discharge scores for Hamilton Depression Rating Scale (HAMD), Young Mania Rating Scale (YMRS), Clinical Global Impressions-Severity for Symptoms (CGI-S), and Dynamic Appraisal of Situational Aggression (DASA) were predicted by treatment condition (i.e., DBT and TAU) while co-varying for admission scores and using a test for CGI-Improvement (CGI-I) in functioning, which was administered upon discharge. Patients who received DBT had significantly lower HAMD scores, (1, 409) = 5.272, = 0.022, = 0.013, and lower CGI-I scores, (596) = 2.50, = 0.00 upon discharge when controlling for admission scores, compared with patients who received TAU. ANCOVAs showed no significant differences on the YMRS, CGI-S, or DASA between the DBT and TAU groups. DBT on an acute-care inpatient unit for adolescents seems to significantly decrease depressive symptoms during a relatively short period of time compared with TAU. DBT may be an effective treatment modality to decrease depressive symptoms for acute-care inpatient units for adolescents.
研究表明,辩证行为疗法(DBT)是一种有效的治疗方法,可以减少青少年门诊人群的自杀意念、非自杀性自伤行为和自杀企图。然而,关于 DBT 对青少年和住院环境中抑郁和躁狂症状的影响的研究有限。本研究旨在检验 DBT 是否与常规治疗(TAU)相比,能显著降低住院青少年的抑郁和躁狂症状。我们对接受住院 DBT 的青少年和同一病房接受 DBT 前的历史对照组(即 TAU)进行了回顾性图表审查。采用协方差分析(ANCOVA)分析连续结果的组间差异,其中汉密尔顿抑郁评定量表(HAMD)、Young 躁狂评定量表(YMRS)、症状临床总体印象严重程度(CGI-S)和动态情境评估(DASA)的出院评分由治疗条件(即 DBT 和 TAU)预测,同时协变量为入院评分,并在出院时进行功能 CGI-改善(CGI-I)测试。接受 DBT 的患者的 HAMD 评分显著降低,(1, 409)= 5.272, = 0.022, = 0.013,CGI-I 评分也显著降低,(596)= 2.50, = 0.00,这是在控制入院评分的情况下与接受 TAU 的患者相比。ANCOVA 显示 DBT 组和 TAU 组在 YMRS、CGI-S 或 DASA 上无显著差异。在急性住院病房,与 TAU 相比,DBT 在青少年中似乎能在相对较短的时间内显著降低抑郁症状。DBT 可能是一种有效的治疗方法,可以减少急性住院病房青少年的抑郁症状。