追踪侵袭性真菌感染的起源。
Tracing the Origin of Invasive Fungal Infections.
机构信息
Host-Pathogen Interaction Study Group (GEIHP, EA 3142), UNIV Angers, UNIV Brest, SFR 4208 ICAT, Angers, France.
Fungal Biology and Pathogenicity Unit, Department of Mycology, Institut Pasteur, Paris, France; University of Paris, Medical School, APHP, Necker-Enfants Malades Hospital, Parasitology Mycology Unit, Department of Microbiology, Paris, France.
出版信息
Trends Microbiol. 2020 Apr;28(4):240-242. doi: 10.1016/j.tim.2020.01.007. Epub 2020 Feb 7.
Invasive fungal infections are a major cause of mortality in immunocompromised patients. By using high-resolution sequencing, Zhai et al. provide insight into translocation of Candida strains from the gut mycobiota to the bloodstream of transplanted patients. Microbiota-driven diagnostic methods could rapidly emerge for preventing deadly fungal infections.
侵袭性真菌感染是免疫功能低下患者死亡的主要原因。翟等通过高分辨率测序，深入了解了肠道真菌区系中的假丝酵母菌向移植患者血流的易位。基于微生物组的诊断方法可能会迅速出现，以预防致命的真菌感染。
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