State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, China.
State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Animal Virology of the Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu 730000, China.
Chem Commun (Camb). 2020 Mar 10;56(20):3003-3006. doi: 10.1039/c9cc09878j.
In this study, an efficient strategy for the synthesis of dumbbell-shaped amphiphilic copolymers with cyclic moieties as the two bells was developed and the enhanced performance of dumbbell-shaped copolymers for controlled drug release because of the simultaneous introduction of two macrocycles was disclosed.
在这项研究中,开发了一种有效的方法来合成哑铃形两亲嵌段共聚物,其中环状结构作为两个哑铃。同时引入两个大环,揭示了哑铃形共聚物在控制药物释放方面的增强性能。