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老年人在入住养老院前后精神药物的配给情况。

The dispensing of psychotropic medicines to older people before and after they enter residential aged care.

机构信息

Registry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, SA.

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom.

出版信息

Med J Aust. 2020 Apr;212(7):309-313. doi: 10.5694/mja2.50501. Epub 2020 Feb 11.

Abstract

OBJECTIVE

To examine the prevalence of psychotropic medicine dispensing before and after older people enter residential care.

DESIGN

Retrospective national cohort study; analysis of Registry of Senior Australians (ROSA) data.

SETTING, PARTICIPANTS: All concession card-holding residents of government-subsidised residential aged care facilities in Australia who entered residential care for at least three months between 1 April 2008 and 30 June 2015.

MAIN OUTCOME MEASURES

Proportions of residents dispensed antipsychotic, benzodiazepine, or antidepressant medicines during the year preceding and the year after commencing residential care, by quarter.

RESULTS

Of 322 120 included aged care residents, 68 483 received at least one antipsychotic (21.3%; 95% CI, 21.1-21.4%), 98 315 at least one benzodiazepine (30.5%; 95% CI, 30.4-30.7%), and 122 224 residents at least one antidepressant (37.9%; 95% CI, 37.8-38.1%) during their first three months of residential care; 31 326 of those dispensed antipsychotics (45.7%), 38 529 of those dispensed benzodiazepines (39.2%), and 25 259 residents dispensed antidepressants (19.8%) had not received them in the year preceding their entry into care. During the first three months of residential care, the prevalence of antipsychotic (prevalence ratio [PR], 3.37; 95% CI, 3.31-3.43) and antidepressant dispensing (PR, 1.05; 95% CI, 1.04-1.07) were each higher for residents with than for those without dementia; benzodiazepine dispensing was similar for both groups (PR, 1.01; 95% CI, 0.99-1.02).

CONCLUSIONS

Dispensing of psychotropic medicines to older Australians is high before they enter residential care but increases markedly soon after entry into care. Non-pharmacological behavioural management strategies are important for limiting the prescribing of psychotropic medicines for older people in the community or in residential care.

摘要

目的

调查老年人入住养老院前后精神药物配药的流行情况。

设计

回顾性全国队列研究;对澳大利亚老年人登记处(ROSA)数据的分析。

地点、参与者:2008 年 4 月 1 日至 2015 年 6 月 30 日期间,在澳大利亚政府补贴的养老院中至少入住三个月的持有优惠卡的所有居民。

主要观察指标

在入住养老院前一年和后一年,按季度计算服用抗精神病药、苯二氮䓬类或抗抑郁药的居民比例。

结果

在纳入的 322 120 名养老院居民中,68 483 人(21.3%;95%CI,21.1-21.4%)至少服用了一种抗精神病药,98 315 人(30.5%;95%CI,30.4-30.7%)至少服用了一种苯二氮䓬类药物,122 224 人(37.9%;95%CI,37.8-38.1%)在入住养老院的前三个月内至少服用了一种抗抑郁药;在服用抗精神病药的 31 326 人中(45.7%),在服用苯二氮䓬类药物的 38 529 人中(39.2%),以及在服用抗抑郁药的 25 259 名居民中(19.8%),在入住养老院前一年没有服用过这些药物。在养老院居住的前三个月,与无痴呆症的居民相比,抗精神病药(患病率比 [PR],3.37;95%CI,3.31-3.43)和抗抑郁药(PR,1.05;95%CI,1.04-1.07)的配药率更高;两组的苯二氮䓬类药物配药率相似(PR,1.01;95%CI,0.99-1.02)。

结论

在进入养老院之前,澳大利亚老年人服用精神药物的比例很高,但在进入养老院后不久就显著增加。对于社区或养老院中的老年人,非药物行为管理策略对于限制精神药物的处方非常重要。

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