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头孢泊肟酯干混悬剂治疗呼吸道感染的临床研究

[Clinical studies of cefpodoxime proxetil in respiratory tract infections].

作者信息

Odagiri S, Matsunaga K, Suzuki K, Murohashi K, Takahashi H, Numata H, Takahashi K, Yamaki I, Ishii S

机构信息

Department of Respiratory Disease, Kanagawa Prefectual Nagahama Hospital.

出版信息

Jpn J Antibiot. 1988 Oct;41(10):1538-44.

PMID:3204658
Abstract

Twelve patients with respiratory tract infections were treated with cefpodoxime proxetil (CS-807, CPDX-PR), a new cephem antibiotic. It was given orally at a dose of 200 mg 2 times a day for 4 approximately 15 days. Its clinical effects were evaluated as excellent in 1 case, good in 9 cases and poor in 2 cases. The efficacy rate was 83.3%. Its bacteriological effects were evaluated as eradication in 5 strains and decrement in 1 strain. The eradication rate was 83.3%. No adverse reactions and disorder of laboratory findings due to CPDX-PR were observed.

摘要

12例呼吸道感染患者接受了新的头孢烯类抗生素头孢泊肟酯(CS - 807,CPDX - PR)治疗。口服给药,剂量为200mg,每日2次,疗程约4至15天。临床疗效评估为:优1例,良9例,差2例。有效率为83.3%。细菌学疗效评估为:5株菌清除,1株菌减少。清除率为83.3%。未观察到因CPDX - PR引起的不良反应及实验室检查异常。

相似文献

1
[Clinical studies of cefpodoxime proxetil in respiratory tract infections].头孢泊肟酯干混悬剂治疗呼吸道感染的临床研究
Jpn J Antibiot. 1988 Oct;41(10):1538-44.
2
[Clinical evaluation of cefpodoxime proxetil in the treatment of skin and soft tissue infections. A double blind comparison of cefpodoxime proxetil and cefaclor].头孢泊肟酯治疗皮肤及软组织感染的临床评价。头孢泊肟酯与头孢克洛的双盲比较
Jpn J Antibiot. 1988 Oct;41(10):1517-37.
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[Pharmacokinetic and clinical studies on cefpodoxime proxetil dry syrup in the field of pediatrics].头孢泊肟酯干糖浆在儿科领域的药代动力学及临床研究
Jpn J Antibiot. 1989 Jul;42(7):1629-66.
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[Bacteriological, pharmacokinetic and clinical studies on cefpodoxime proxetil in the pediatric field].头孢泊肟酯在儿科领域的细菌学、药代动力学及临床研究
Jpn J Antibiot. 1989 Jul;42(7):1593-606.
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[Clinical evaluation of a new oral cephem, cefpodoxime proxetil in children].[新型口服头孢菌素头孢泊肟酯干混悬剂在儿童中的临床评价]
Jpn J Antibiot. 1989 Jul;42(7):1561-70.
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Jpn J Antibiot. 1993 Jan;46(1):53-9.
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[Clinical studies on cefpodoxime proxetil in the pediatric fields].头孢泊肟酯在儿科领域的临床研究
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引用本文的文献

1
Summary of clinical experience with cefpodoxime proxetil in adults in Japan.
Drugs. 1991;42 Suppl 3:1-5. doi: 10.2165/00003495-199100423-00003.