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Combining haplo-identical and cord blood stem cell grafts - might the whole be greater than the sum of its parts?

作者信息

Orfali Nina, van Besien Koen

机构信息

Department of Bone Marrow Transplantation, Weill Cornell Medicine, New York, NY, USA.

出版信息

Leuk Lymphoma. 2020 Apr;61(4):753-756. doi: 10.1080/10428194.2020.1725509. Epub 2020 Feb 12.

DOI:10.1080/10428194.2020.1725509
PMID:32048529
Abstract
摘要

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1
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2
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Reduced-Intensity Allogeneic Transplant for Acute Myeloid Leukemia and Myelodysplastic Syndrome Using Combined CD34-Selected Haploidentical Graft and a Single Umbilical Cord Unit Compared with Matched Unrelated Donor Stem Cells in Older Adults.采用 CD34 分选的单倍体相合移植物联合单个脐带来源的造血干细胞与非血缘供者造血干细胞比较,用于治疗老年急性髓系白血病和骨髓增生异常综合征的减低强度异基因移植。
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Hematopoietic stem cell transplant with HLA-mismatched grafts: impact of donor, source, conditioning, and graft versus host disease prophylaxis.造血干细胞移植与 HLA 不匹配供体:供体、来源、预处理和移植物抗宿主病预防的影响。
Expert Rev Hematol. 2019 Jan;12(1):47-60. doi: 10.1080/17474086.2019.1562331. Epub 2018 Dec 29.
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Haploidentical cord transplantation-The best of both worlds.单倍体相合脐带血移植——两全其美。
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引用本文的文献

1
A Prospective Trial Comparing Haploidentical Donor Transplantation With Cord Blood Versus HLA-Matched Sibling Donor Transplantation for Hematologic Malignancy Patients.一项比较单倍体相合供者移植与脐带血移植和 HLA 匹配同胞供者移植治疗血液系统恶性肿瘤患者的前瞻性试验。
Cell Transplant. 2022 Jan-Dec;31:9636897221076050. doi: 10.1177/09636897221076050.