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一项比较单倍体相合供者移植与脐带血移植和 HLA 匹配同胞供者移植治疗血液系统恶性肿瘤患者的前瞻性试验。

A Prospective Trial Comparing Haploidentical Donor Transplantation With Cord Blood Versus HLA-Matched Sibling Donor Transplantation for Hematologic Malignancy Patients.

机构信息

Department of Hematology, Tianjin First Central Hospital, Tianjin, PR China.

Nankai University Affiliated First Central Hospital, Tianjin, PR China.

出版信息

Cell Transplant. 2022 Jan-Dec;31:9636897221076050. doi: 10.1177/09636897221076050.

DOI:10.1177/09636897221076050
PMID:35168385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8855410/
Abstract

Effect of co-infusion third party umbilical cord blood stem cells on haploidentical hematopoietic stem cell transplantation https://www.chictr.org.cn Reg. No. ChiCTR-OIN-17011426.

摘要

第三方脐血干细胞共输注对单倍体造血干细胞移植的影响 [www.chictr.org.cn 注册号 ChiCTR-OIN-17011426]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/63d44079caf7/10.1177_09636897221076050-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/40748bffcc11/10.1177_09636897221076050-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/8e43b861abd5/10.1177_09636897221076050-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/784cf8a025e3/10.1177_09636897221076050-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/2a89ef7b2a7e/10.1177_09636897221076050-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/63d44079caf7/10.1177_09636897221076050-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/40748bffcc11/10.1177_09636897221076050-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/8e43b861abd5/10.1177_09636897221076050-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/784cf8a025e3/10.1177_09636897221076050-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/2a89ef7b2a7e/10.1177_09636897221076050-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b6/8855410/63d44079caf7/10.1177_09636897221076050-fig5.jpg

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本文引用的文献

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Cancer Med. 2020 Sep;9(17):6244-6255. doi: 10.1002/cam4.3290. Epub 2020 Jul 20.
2
Engraftment kinetics after transplantation of double unit cord blood grafts combined with haplo-identical CD34+ cells without antithymocyte globulin.双份脐血移植联合未经抗胸腺细胞球蛋白的单倍体相合 CD34+细胞后的植入动力学。
Leukemia. 2021 Mar;35(3):850-862. doi: 10.1038/s41375-020-0922-x. Epub 2020 Jun 18.
3
Combination of haploidentical haematopoietic stem cell transplantation with an unrelated cord-blood unit in patients with severe aplastic anemia: a report of 146 cases.
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Bone Marrow Transplant. 2020 Oct;55(10):2017-2025. doi: 10.1038/s41409-020-0874-9. Epub 2020 Mar 26.
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Bone Marrow Transplant. 2020 Jun;55(6):1197-1199. doi: 10.1038/s41409-019-0666-2. Epub 2019 Sep 5.
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Outcomes of allogeneic haematopoietic stem cell transplantation from HLA-matched and alternative donors: a European Society for Blood and Marrow Transplantation registry retrospective analysis.来自HLA匹配供者和替代供者的异基因造血干细胞移植的结局:欧洲血液与骨髓移植学会登记处的回顾性分析
Lancet Haematol. 2019 Nov;6(11):e573-e584. doi: 10.1016/S2352-3026(19)30158-9. Epub 2019 Aug 30.
9
Haploidentical vs haplo-cord transplant in adults under 60 years receiving fludarabine and melphalan conditioning.成人患者接受氟达拉滨和马法兰预处理后行haploidentical 与haplo-cord 移植的比较。
Blood Adv. 2019 Jun 25;3(12):1858-1867. doi: 10.1182/bloodadvances.2019000200.
10
Comparison of outcomes in hematological malignancies treated with haploidentical or HLA-identical sibling hematopoietic stem cell transplantation following myeloablative conditioning: A meta-analysis.清髓性预处理后单倍体相合或 HLA 全相合同胞造血干细胞移植治疗血液系统恶性肿瘤的疗效比较:一项荟萃分析。
PLoS One. 2018 Jan 30;13(1):e0191955. doi: 10.1371/journal.pone.0191955. eCollection 2018.