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低资源环境下的生物样本库应当如何管理?

How Should Biobanking Be Governed in Low-Resource Settings?

机构信息

An associate professor of bioethics in the Department of Medicine at the University of Cape Town in South Africa.

出版信息

AMA J Ethics. 2020 Feb 1;22(2):E156-163. doi: 10.1001/amajethics.2020.156.

Abstract

Development of biobanks in Africa raises ethical questions related to particular features of African cancer research contexts, such as underresourced health care and research infrastructures and low-average research literacy. This article describes ethical challenges of informed consent, benefit sharing, and stigmatization and proposes navigating these challenges by developing a comprehensive governance framework to ensure African leadership in biobanking research programs in Africa.

摘要

非洲生物银行的发展引发了与非洲癌症研究背景的特殊特征相关的伦理问题,例如医疗资源和研究基础设施不足以及研究素养普遍较低。本文描述了知情同意、利益分享和污名化的伦理挑战,并提出通过制定全面的治理框架来应对这些挑战,以确保非洲在非洲生物库研究计划中发挥领导作用。

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