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泌尿生殖道肿瘤患者的免疫反应:通过淋巴细胞激活试验对细胞介导的抗肿瘤免疫进行随访。

Immunological response of patients with tumors of the urogenital tract: a follow-up of cell-mediated antitumor immunity by the LAI test.

作者信息

Holán V, Heyberger K, Bubeník J, Hasek M, Kanka J, Laurová L

出版信息

Neoplasma. 1977;24(1):71-9.

PMID:320490
Abstract

Antigen-induced inhibition of leukocyte adherence is a suitable method providing information on immunological response of the tumor bearers. Leukocytes from patients' blood were tested by an in vitro method to detect cell-mediated antitumor immunity. Positive reactions of leukocytes to the specific antigen were found in carcinoma of the uterine cervix, vulva and ovary in 13 patients. The modified LAI test evaluated on the basis of free cells in Eagle's medium using the specific antigen is a simplified reversed method which, however, keeps the specificity.

摘要

抗原诱导的白细胞黏附抑制是一种适用于提供肿瘤患者免疫反应信息的方法。通过体外方法检测患者血液中的白细胞,以检测细胞介导的抗肿瘤免疫。在13例子宫颈癌、外阴癌和卵巢癌患者中发现白细胞对特异性抗原呈阳性反应。基于伊格尔培养基中游离细胞并使用特异性抗原进行评估的改良白细胞黏附抑制试验是一种简化的反向方法,但仍保持特异性。

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