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化脓性汗腺炎手术干预后并发症和复发的系统评价。

Systematic Review of Complications and Recurrences After Surgical Interventions in Hidradenitis Suppurativa.

机构信息

Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.

Department of Clinical Medicine, Health Sciences Faculty, University of Copenhagen, Copenhagen, Denmark.

出版信息

Dermatol Surg. 2020 Jul;46(7):914-921. doi: 10.1097/DSS.0000000000002323.

Abstract

BACKGROUND

The possible connection between hidradenitis suppurativa (HS) patients undergoing surgery and higher complications/recurrences has been implied, but inconsistent results reported.

OBJECTIVE

To assess the complication and recurrence rates for HS patients undergoing surgery and to evaluate whether known HS comorbidities and habits (smoking, obesity and diabetes) have an effect on the complication and recurrence rates.

MATERIALS AND METHODS

A systematic review was conducted by 2 reviewers. PubMed and Embase were searched using a predefined search string created in collaboration between the authors and a librarian on January 23, 2019.

RESULTS

Of the 271 references in the original search, 54 relevant articles were identified. This systematic review indicates an overall mean complication rate of 24% and a mean recurrence rate of 20.1% for HS patients undergoing surgery.

CONCLUSION

No significant association between the known surgical risk factors and surgical complications-or recurrence rates in this patient group was found. This review revealed a lack of quality and quantity data in studying the complications/recurrences. The heterogeneity of the studies created limitations, and the presented mean complication/recurrence rates should be interpreted with the consequences thereof. It elucidates the need for better studies and a necessity for a standardized definition of postsurgical HS recurrence.

摘要

背景

患有化脓性汗腺炎(HS)并接受手术的患者可能会出现更高的并发症/复发率,这一点已被暗示,但报道的结果并不一致。

目的

评估接受手术的 HS 患者的并发症和复发率,并评估已知的 HS 合并症和习惯(吸烟、肥胖和糖尿病)是否对并发症和复发率有影响。

材料和方法

两位审阅者进行了系统评价。2019 年 1 月 23 日,作者和一名图书管理员合作使用预定义的搜索字符串在 PubMed 和 Embase 上进行了搜索。

结果

在最初的搜索中,有 271 篇参考文献,其中有 54 篇相关文章被确定。本系统评价表明,接受手术的 HS 患者的总体平均并发症发生率为 24%,平均复发率为 20.1%。

结论

在该患者群体中,未发现已知手术危险因素与手术并发症或复发率之间存在显著关联。本综述显示,研究并发症/复发的质量和数量数据均不足。研究的异质性带来了局限性,所呈现的平均并发症/复发率应考虑其带来的后果。这阐明了需要进行更好的研究以及对术后 HS 复发进行标准化定义的必要性。

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