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体力活动在绝经状况和心理健康之间的关联中的作用。

The role of physical activity in the link between menopausal status and mental well-being.

机构信息

Gerontology Research Center and Faculty of Sport and Health Sciences, University of Jyvaskyla, Finland.

Neuromuscular Research Center, Faculty of Sport and Health Sciences, University of Jyvaskyla, Finland.

出版信息

Menopause. 2020 Apr;27(4):398-409. doi: 10.1097/GME.0000000000001490.

Abstract

OBJECTIVE

To examine the relationship between menopausal status and mental well-being, and whether this relationship varies as a function of physical activity (PA).

METHODS

Based on a hormonal analysis and bleeding diary, women aged 47 to 55 were categorized as pre (n = 304), early peri (n = 198), late peri (n = 209), or postmenopausal (n = 387). Mental well-being was assessed using the Centre for Epidemiologic Studies Depression Scale, the International Positive and Negative Affect Schedule Short Form, and the Satisfaction with Life Scale. PA was self-reported and categorized as low, medium, and high. Associations between variables were analyzed using multivariate linear regression adjusted for age, marital and employment status, parity, self-reported mental disorder, use of psycholeptics and psychoanaleptics, and menopausal symptoms.

RESULTS

Depressive symptoms were lower amongst the pre than postmenopausal women (B = 0.07, confidence interval 0.01-0.13). Menopausal symptoms attenuated these associations. Menopausal status showed no associations with life satisfaction, or with positive or negative affectivity.Women with high PA scored higher on positive affectivity, and the pre, early peri, and postmenopausal women scored higher on life satisfaction (B = 0.79, P < 0.001; B = 0.63, P = 0.009; B = 0.42, P = 0.009, respectively) and scored lower on depressive symptoms (B = -0.13, P = 0.039; B = -0.18, P = 0.034; and B = -0.20, P < 0.001, respectively) than their low PA counterparts. The pre and postmenopausal women with medium PA scored higher on life satisfaction (B = 0.54, P = 0.001; B = 0.038, P = 0.004, respectively) than those with low PA.

CONCLUSIONS

Postmenopausal women reported marginally higher depressive symptoms scores compared with premenopausal women, but menopause was not associated with positive mental well-being. However, this association varies with the level of PA. : Video Summary:http://links.lww.com/MENO/A520.

摘要

目的

探讨绝经状态与心理健康的关系,以及这种关系是否因体力活动(PA)而有所不同。

方法

基于激素分析和出血日记,将 47 至 55 岁的女性分为绝经前(n=304)、早绝经(n=198)、晚绝经(n=209)或绝经后(n=387)。使用流行病学研究抑郁量表、国际正性和负性情绪量表简短版和生活满意度量表评估心理健康。体力活动为自我报告,分为低、中、高。使用多变量线性回归分析调整年龄、婚姻和就业状况、生育次数、自我报告的精神障碍、精神药物和精神兴奋药物的使用以及绝经症状等因素后,分析变量之间的相关性。

结果

与绝经后妇女相比,绝经前妇女的抑郁症状评分较低(B=0.07,置信区间 0.01-0.13)。绝经症状减弱了这些关联。绝经状态与生活满意度或正性或负性情感无关联。PA 较高的女性正性情感得分较高,绝经前、早期绝经和绝经后女性生活满意度得分较高(B=0.79,P<0.001;B=0.63,P=0.009;B=0.42,P=0.009),抑郁症状得分较低(B=-0.13,P=0.039;B=-0.18,P=0.034;B=-0.20,P<0.001)。PA 中等的绝经前和绝经后女性生活满意度得分高于 PA 较低的女性(B=0.54,P=0.001;B=0.038,P=0.004)。

结论

与绝经前女性相比,绝经后女性报告的抑郁症状评分略高,但绝经与积极的心理健康无关。然而,这种关联因 PA 水平而异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4433/7147406/922a084d196c/menop-27-398-g001.jpg

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