Department of Gastroenterology, Hashimoto Municipal Hospital, Hashimoto, Wakayama, Japan.
Department of Cardiology, Hashimoto Municipal Hospital, Hashimoto, Wakayama, Japan.
PLoS One. 2020 Feb 12;15(2):e0228117. doi: 10.1371/journal.pone.0228117. eCollection 2020.
The parasympathetic nervous system exerts and controls intestinal tone. Several studies have suggested that the coefficient of the R-R intervals (CVRR) is useful for evaluating the parasympathetic nervous system.
This study aimed to evaluate the relationship between gastrointestinal emergencies, specifically ischemic colitis (IC) and small bowel obstruction (SBO), and the autonomic nervous system.
In this retrospective study, a total of 13 patients with IC or SBO aged ≧65 years were analyzed. CVRR was measured in patients with IC and SBO and controls.
CVRR averaged to 8.8% ± 2.5% in controls, 1.4% ± 0.4% in patients with IC, and 2.4% ± 1.0% in SBO groups (p < 0.001). CVRR was significantly lower in patients with IC and SBO than that in controls.
The results of this study demonstrate the possibility that CVRR may serve as a clinical index for assessing the functioning of the parasympathetic nervous system in patients with IC or SBO.
副交感神经系统对肠道张力具有支配和控制作用。有几项研究表明，R-R 间期系数（CVRR）可用于评估副交感神经系统。
本研究旨在评估胃肠道急症，特别是缺血性结肠炎（IC）和小肠梗阻（SBO）与自主神经系统之间的关系。
在这项回顾性研究中，共分析了 13 名年龄≧65 岁的 IC 或 SBO 患者。对 IC 和 SBO 患者以及对照组患者进行了 CVRR 测量。
对照组的 CVRR 平均值为 8.8%±2.5%，IC 组为 1.4%±0.4%，SBO 组为 2.4%±1.0%（p<0.001）。IC 和 SBO 患者的 CVRR 明显低于对照组。
本研究结果表明，CVRR 可能成为评估 IC 或 SBO 患者副交感神经系统功能的临床指标。
