Department of Respiratory Disease, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
Department of Pathology, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
Respiration. 2020;99(5):426-430. doi: 10.1159/000505936. Epub 2020 Feb 12.
Mediastinal biopsy is essential for the clinical diagnosis of mediastinal disease. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a well-established approach for obtaining diagnostic samples from mediastinal masses or enlarged lymph nodes which is proven to be minimally invasive and effective. However, the insufficiency of intact samples acquired might restrict the diagnostic efficacy of EBUS-TBNA for mediastinal lesions such as rare malignancy and granulomatous disorder. We here present an EBUS-guided approach for the cryobiopsy of mediastinal diseases that is capable of providing larger amounts of intact tissue with few observed complications.
纵隔活检对于纵隔疾病的临床诊断至关重要。经支气管超声引导下经支气管针吸活检术（EBUS-TBNA）是一种从纵隔肿块或肿大淋巴结获取诊断样本的成熟方法，已被证明具有微创和有效的特点。然而，获取的完整样本不足可能会限制 EBUS-TBNA 对纵隔病变（如罕见恶性肿瘤和肉芽肿性疾病）的诊断效果。我们在此介绍了一种经支气管超声引导下的纵隔疾病冷冻活检方法，该方法能够提供更多数量的完整组织，且观察到的并发症较少。
