Department of Otolaryngology, Renmin Hospital, 74765Hubei University of Medicine, Shiyan, Hubei, China.
Department of Otolaryngology-Head and Neck Surgery, Hospital Affiliated to Ningxia Medical University, Yinchuan, China.
Ear Nose Throat J. 2021 Sep;100(5_suppl):684S-690S. doi: 10.1177/0145561320902859. Epub 2020 Feb 13.
To investigate the effect of drug treatment combined with psychological intervention on mental disorders in patients with persistent moderate-severe allergic rhinitis.
Sixty patients with persistent moderate-severe allergic rhinitis who met the criteria were randomly divided into 2 groups: control group and experimental group. The control group was only given medication, whereas the experimental group was given psychological intervention on the basis of the same medication. Cognitive behavioral therapy was used for psychological intervention. After 12 weeks of treatment, Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), and rhinoconjunctivitis quality of life questionnaire (RQLQ) were used to evaluate the changes in anxiety, depression, and quality of life before and after treatment.
The SAS and SDS scores of the control group after treatment were lower than those before treatment, and the difference was statistically significant. Similarly, the SAS and SDS scores of the experimental group after treatment were lower than those before treatment with statistically significant difference. In addition, after treatment, the SAS and SDS scores of the experimental group were statistically lower than those of the control group. The results of RQLQ showed that the scores of each dimension in the control group after treatment were lower than those before treatment, and the difference was statistically significant. Similar results were found in the experimental group. After treatment with these 2 different schemes, the RQLQ scores of sleep, nonnasal/eye symptoms, and emotion in the experimental group were statistically lower than those in the control group.
Drug therapy or drug therapy combined with psychological intervention can alleviate anxiety and depression of patients with persistent moderate-severe allergic rhinitis and improve their quality of life. Moreover, based on the effect of improving mental disorder and quality of life of patients, drug therapy combined with psychological intervention is better than drug treatment alone.
探讨药物治疗联合心理干预对持续性中重度变应性鼻炎患者精神障碍的影响。
将符合标准的 60 例持续性中重度变应性鼻炎患者随机分为 2 组:对照组和实验组。对照组仅给予药物治疗,实验组在相同药物治疗的基础上给予心理干预。心理干预采用认知行为疗法。治疗 12 周后,采用焦虑自评量表(SAS)、抑郁自评量表(SDS)和变应性鼻炎生活质量问卷(RQLQ)评估治疗前后焦虑、抑郁和生活质量的变化。
对照组治疗后 SAS 和 SDS 评分低于治疗前,差异有统计学意义。实验组治疗后 SAS 和 SDS 评分亦低于治疗前,差异有统计学意义。此外,治疗后实验组 SAS 和 SDS 评分均低于对照组,差异有统计学意义。RQLQ 结果显示,对照组治疗后各维度评分均低于治疗前,差异有统计学意义。实验组也有类似结果。采用这 2 种不同方案治疗后,实验组睡眠、非鼻/眼症状和情绪维度的 RQLQ 评分均低于对照组。
药物治疗或药物治疗联合心理干预均可缓解持续性中重度变应性鼻炎患者的焦虑和抑郁,提高其生活质量。而且,药物治疗联合心理干预在改善患者精神障碍和生活质量方面优于单纯药物治疗。