吸烟与中年人群的脑血流。
Cigarette smoking and cerebral blood flow in a cohort of middle-aged adults.
机构信息
Department of Neurology, Neurobiology Research Unit, Rigshospitalet, Copenhagen, Denmark.
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
出版信息
J Cereb Blood Flow Metab. 2020 Apr;40(4):904-905. doi: 10.1177/0271678X20905609. Epub 2020 Feb 12.
Abstract
Cigarette smoking increases cerebral blood flow. Both nicotine and carbon monoxide contribute to the flow increase. Due to carbon monoxide’s high affinity to hemoglobin and slow clearance from the blood, the effect lasts for hours. Nicotine also stays in the organism for some hours. This immediate effect of smoking may explain a recently observed higher cerebral blood flow in current-smokers as compared to former-smokers.
摘要
吸烟会增加脑血流量。尼古丁和一氧化碳都有助于增加血流量。由于一氧化碳与血红蛋白的亲和力高，从血液中清除速度较慢，因此这种作用会持续数小时。尼古丁在体内也会停留数小时。吸烟的这种即时效应可能解释了最近观察到的吸烟者比戒烟者的脑血流更高的现象。
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