Department of Orthopaedics, Colchester General Hospital, Turner Road, Mile End, Colchester, Essex, CO4 5JL, UK.
Imperial College London, London, UK.
BMC Musculoskelet Disord. 2020 Feb 12;21(1):95. doi: 10.1186/s12891-020-3100-4.
The ideal thromboprophylaxis regime following lower limb arthroplasty and proximal femur fractures remains controversial. Guidelines disagree on the type of chemical prophylaxis, its dose or duration. This article describes a method of monitoring venous thromboembolism (VTE) rates following Total Hip (THA), Total Knee Arthroplasty (TKA) and surgery for hip fractures (NOF#).
Over 3 years, all patients investigated for VTE were analysed using Picture Archiving Communications System (PACS). All positive scans were then cross-referenced using PACS and local registry data to see if they had undergone THA, TKA or NOF# in the preceding 90 days. Mortality data were obtained from the national administrative database, Hospital Episode Statistics.
Five thousand seven hundred eighty-eight patients underwent investigation for VTE and there were 29 diagnoses of PE and 24 of DVT. There was a 0.77% rate of symptomatic DVT after THA, 0.05% after TKA and 0.55% after NOF #. The rate of confirmed symptomatic PE for THA was 0.46, 0.27% for TKA and 0.96% for NOF #. Mortality at one-year post-THA was 0.6, 0.6% for TKA and 25.9% after NOF#. All patients contacted either remained within the catchment area for the minimum 90 postoperative days or died within the catchment area.
The 90 day post-operative prevalence of symptomatic VTE of 1.2, 0.3 and 1.5% in THA, TKA and NOF # respectively are similar to other studies using symptomatic and imaging positive VTE as their endpoint. The study uses a method of collecting data which can be utilised in centres where PACS is available.
下肢关节置换和股骨近端骨折后理想的血栓预防方案仍存在争议。指南在化学预防的类型、剂量或持续时间上存在分歧。本文描述了一种监测全髋关节置换术(THA)、全膝关节置换术(TKA)和髋部骨折(NOF#)术后静脉血栓栓塞症(VTE)发生率的方法。
在 3 年期间,使用影像归档与通信系统(PACS)对所有接受 VTE 检查的患者进行分析。然后,使用 PACS 和当地登记数据对所有阳性扫描进行交叉引用,以确定他们是否在之前的 90 天内接受过 THA、TKA 或 NOF#。死亡率数据从国家行政数据库(医院入院统计数据)中获得。
5788 例患者接受了 VTE 检查,其中 29 例诊断为 PE,24 例诊断为 DVT。THA 后有 0.77%的症状性 DVT 发生率,TKA 后为 0.05%,NOF#后为 0.55%。THA 确诊症状性 PE 的发生率为 0.46%,TKA 为 0.27%,NOF#为 0.96%。THA 后 1 年的死亡率为 0.6%,TKA 为 0.6%,NOF#为 25.9%。所有患者均在术后 90 天内留在了研究区域内,或在研究区域内死亡。
THA、TKA 和 NOF#术后 90 天症状性 VTE 的发生率分别为 1.2%、0.3%和 1.5%,与其他使用症状性和影像学阳性 VTE 作为终点的研究相似。该研究使用了一种可以在有 PACS 的中心收集数据的方法。