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髋关节和膝关节置换术及髋部骨折后的静脉血栓栓塞发生率。

Venous thromboembolism rates after hip and knee arthroplasty and hip fractures.

机构信息

Department of Orthopaedics, Colchester General Hospital, Turner Road, Mile End, Colchester, Essex, CO4 5JL, UK.

Imperial College London, London, UK.

出版信息

BMC Musculoskelet Disord. 2020 Feb 12;21(1):95. doi: 10.1186/s12891-020-3100-4.

Abstract

BACKGROUND

The ideal thromboprophylaxis regime following lower limb arthroplasty and proximal femur fractures remains controversial. Guidelines disagree on the type of chemical prophylaxis, its dose or duration. This article describes a method of monitoring venous thromboembolism (VTE) rates following Total Hip (THA), Total Knee Arthroplasty (TKA) and surgery for hip fractures (NOF#).

METHODS

Over 3 years, all patients investigated for VTE were analysed using Picture Archiving Communications System (PACS). All positive scans were then cross-referenced using PACS and local registry data to see if they had undergone THA, TKA or NOF# in the preceding 90 days. Mortality data were obtained from the national administrative database, Hospital Episode Statistics.

RESULTS

Five thousand seven hundred eighty-eight patients underwent investigation for VTE and there were 29 diagnoses of PE and 24 of DVT. There was a 0.77% rate of symptomatic DVT after THA, 0.05% after TKA and 0.55% after NOF #. The rate of confirmed symptomatic PE for THA was 0.46, 0.27% for TKA and 0.96% for NOF #. Mortality at one-year post-THA was 0.6, 0.6% for TKA and 25.9% after NOF#. All patients contacted either remained within the catchment area for the minimum 90 postoperative days or died within the catchment area.

CONCLUSIONS

The 90 day post-operative prevalence of symptomatic VTE of 1.2, 0.3 and 1.5% in THA, TKA and NOF # respectively are similar to other studies using symptomatic and imaging positive VTE as their endpoint. The study uses a method of collecting data which can be utilised in centres where PACS is available.

摘要

背景

下肢关节置换和股骨近端骨折后理想的血栓预防方案仍存在争议。指南在化学预防的类型、剂量或持续时间上存在分歧。本文描述了一种监测全髋关节置换术(THA)、全膝关节置换术(TKA)和髋部骨折(NOF#)术后静脉血栓栓塞症(VTE)发生率的方法。

方法

在 3 年期间,使用影像归档与通信系统(PACS)对所有接受 VTE 检查的患者进行分析。然后,使用 PACS 和当地登记数据对所有阳性扫描进行交叉引用,以确定他们是否在之前的 90 天内接受过 THA、TKA 或 NOF#。死亡率数据从国家行政数据库(医院入院统计数据)中获得。

结果

5788 例患者接受了 VTE 检查,其中 29 例诊断为 PE,24 例诊断为 DVT。THA 后有 0.77%的症状性 DVT 发生率,TKA 后为 0.05%,NOF#后为 0.55%。THA 确诊症状性 PE 的发生率为 0.46%,TKA 为 0.27%,NOF#为 0.96%。THA 后 1 年的死亡率为 0.6%,TKA 为 0.6%,NOF#为 25.9%。所有患者均在术后 90 天内留在了研究区域内,或在研究区域内死亡。

结论

THA、TKA 和 NOF#术后 90 天症状性 VTE 的发生率分别为 1.2%、0.3%和 1.5%,与其他使用症状性和影像学阳性 VTE 作为终点的研究相似。该研究使用了一种可以在有 PACS 的中心收集数据的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6073/7017506/9a7a71cabe0d/12891_2020_3100_Fig1_HTML.jpg

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