术前低钠血症是无菌性髋关节和膝关节翻修置换术后并发症的独立危险因素。
Preoperative hyponatremia is an independent risk factor for postoperative complications in aseptic revision hip and knee arthroplasty.
作者信息
Gu Alex, Chen Frank R, Chen Aaron Z, Fassihi Safa C, Thakkar Savyasachi, Unger Anthony S, Liu Jiabin, Sculco Peter K, Ast Michael P
机构信息
Complex Joint Reconstruction Center, Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 E 70th, St, New York, NY, 10021, USA.
The George Washington University School of Medicine, Department of Orthopaedic Surgery, 2300 I St NW, Washington, DC, 20052, USA.
出版信息
J Orthop. 2020 Jan 25;20:224-227. doi: 10.1016/j.jor.2020.01.028. eCollection 2020 Jul-Aug.
INTRODUCTION
The purpose of this study is to investigate the relationship between preoperative hyponatremia and postoperative complications in aseptic revision hip and knee arthroplasty.
METHODS
Aseptic revision arthroplasties from 2007 to 2016 were collected using a large, United States database. Patients were stratified into eunatremic and hyponatremic cohorts. Rates of complications were collected and analyzed.
RESULTS
25,517 surgeries were evaluated. Preoperative hyponatremia was independently associated with organ/space infections (OR= 2.316; p<0.001), postoperative blood transfusions (OR= 1.467; p<0.001), pneumonia (OR= 2.05; p =0.002), sepsis (OR= 2.533; p<0.001), extended length-of-stay (OR= 2.221; p<0.001), minor complications (OR= 1.549; p<0.001), wound complications (OR= 1.505; p=0.001), pulmonary complications (OR= 1.72; p=0.007), and sepsis complications (OR= 2.305; p<0.001).
CONCLUSION
Hyponatremia is an independent risk factor for several postoperative complications in aseptic revision hip and knee arthroplasty.
引言
本研究旨在探讨无菌性髋关节和膝关节翻修术中术前低钠血症与术后并发症之间的关系。
方法
利用一个大型美国数据库收集2007年至2016年的无菌性翻修关节成形术病例。患者被分为血钠正常组和低钠血症组。收集并分析并发症发生率。
结果
共评估了25517例手术。术前低钠血症与器官/腔隙感染（比值比=2.316；p<0.001）、术后输血（比值比=1.467；p<0.001）、肺炎（比值比=2.05；p=0.002）、脓毒症（比值比=2.533；p<0.001）、住院时间延长（比值比=2.221；p<0.001）、轻微并发症（比值比=1.549；p<0.001）、伤口并发症（比值比=1.505；p=0.001）、肺部并发症（比值比=1.72；p=0.007）以及脓毒症并发症（比值比=2.305；p<0.001）独立相关。
结论
低钠血症是无菌性髋关节和膝关节翻修术后多种并发症的独立危险因素。
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