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[门静脉高压时奇静脉血流情况]

[Azygos venous blood flow in portal hypertension].

作者信息

Kokudo N

机构信息

Second Department of Surgery, Faculty of Medicine, University of Tokyo, Japan.

出版信息

Nihon Geka Gakkai Zasshi. 1988 Nov;89(11):1860-8.

PMID:3205251
Abstract

Azygos venous blood flow estimated by the continuous thermodilution method was measured in 48 patients with portal hypertension. In patients with cirrhosis, azygos venous blood flow was 326 +/- 139ml/min (mean SD) and was significantly higher than in patients without portal hypertension (163 +/- 61ml/min). In patients with idiopathic portal hypertension and extrahepatic portal obstruction, azygos venous blood flow was 411 +/- 227ml/min and 328 +/- 85ml/min respectively. Azygos venous blood flow was significantly correlated with the hepatic venous pressure gradient but neither with cardiac output nor with size of esophageal varices. In eleven cirrhotic patients, azygos venous blood flow and other hemodynamic parameters were measured before and after the nonshunting operation of esophageal transection, splenectomy and esophagogastric devascularization. Azygos venous blood flow and hepatic venous pressure gradient were significantly reduced after operation. On the other hand, cardiac output did not change significantly after surgical procedure. Relatively high postoperative azygos venous blood flow indicates its important role in the postoperative collateral circulation.

摘要

采用连续热稀释法对48例门静脉高压患者的奇静脉血流量进行了测定。肝硬化患者的奇静脉血流量为326±139ml/分钟(均值±标准差),显著高于无门静脉高压的患者(163±61ml/分钟)。特发性门静脉高压和肝外门静脉阻塞患者的奇静脉血流量分别为411±227ml/分钟和328±85ml/分钟。奇静脉血流量与肝静脉压力梯度显著相关,但与心输出量和食管静脉曲张大小均无关。对11例肝硬化患者在进行食管横断、脾切除和食管胃去血管化的非分流手术前后测量了奇静脉血流量及其他血流动力学参数。术后奇静脉血流量和肝静脉压力梯度显著降低。另一方面,手术过程中心输出量无显著变化。术后相对较高的奇静脉血流量表明其在术后侧支循环中起重要作用。

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