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[通过测量酒精性肝硬化患者奇静脉血流评估肝门静脉上吻合支的血流情况]

[Evaluation of the blood flow of superior portacaval anastomoses by the measurement of azygos blood flow in patients with alcoholic cirrhosis].

作者信息

Braillon A, Calès P, Jirón M I, Lebrec D

出版信息

Gastroenterol Clin Biol. 1984 Jan;8(1):47-51.

PMID:6698342
Abstract

In patients with portal hypertension the azygos system collects the main part of superior portosystemic shunts; accordingly, azygos blood flow might be a reflection of this collateral circulation. Azygos blood flow, estimated by the continuous thermodilution method with a catheter inserted into the azygos arch, was measured in 20 patients with cirrhosis. The variability of baseline measurements was 6.9 +/- 3.0 p. 100 and the reproducibility was 5.7 +/- 5.8 p. 100. In patients with cirrhosis, azygos blood flow ranged from 0.22 to 1.25 l/min (0.64 /+- 0.30 l/min; mean +/- SD) and was significantly higher than in patients without portal hypertension (0.13 +/- 0.04 l/min). In this series of patients, azygos blood flow was significantly correlated with the hepatic venous pressure gradient but neither with hepatic blood flow nor with cardiac output. This study shows that azygos blood flow may be estimated with the continuous thermodilution method and that azygos blood flow is approximately six times higher in cirrhotic patients than in controls. This result suggests that blood flow through the superior portosystemic shunts is very high.

摘要

在门静脉高压患者中,奇静脉系统收集了大部分的上腔静脉-门静脉分流;因此,奇静脉血流可能反映了这种侧支循环。通过将导管插入奇静脉弓采用连续热稀释法对20例肝硬化患者的奇静脉血流进行了测量。基线测量的变异性为6.9±3.0%,可重复性为5.7±5.8%。肝硬化患者的奇静脉血流范围为0.22至1.25升/分钟(0.64±0.30升/分钟;平均值±标准差),显著高于无门静脉高压的患者(0.13±0.04升/分钟)。在这组患者中,奇静脉血流与肝静脉压力梯度显著相关,但与肝血流量和心输出量均无相关性。本研究表明,采用连续热稀释法可估算奇静脉血流,且肝硬化患者的奇静脉血流比对照组高约6倍。这一结果提示,通过上腔静脉-门静脉分流的血流量非常高。

相似文献

1
[Evaluation of the blood flow of superior portacaval anastomoses by the measurement of azygos blood flow in patients with alcoholic cirrhosis].[通过测量酒精性肝硬化患者奇静脉血流评估肝门静脉上吻合支的血流情况]
Gastroenterol Clin Biol. 1984 Jan;8(1):47-51.
2
[Azygos venous blood flow in portal hypertension].[门静脉高压时奇静脉血流情况]
Nihon Geka Gakkai Zasshi. 1988 Nov;89(11):1860-8.
3
Azygos blood flow: phase contrast quantitation in volunteers and patients with portal hypertension pre- and postintrahepatic shunt placement.奇静脉血流:肝内分流置入前后门静脉高压志愿者和患者的相位对比定量分析
Hepatology. 1996 Nov;24(5):1109-15. doi: 10.1002/hep.510240522.
4
Reduction of variceal pressure by propranolol: comparison of the effects on portal pressure and azygos blood flow in patients with cirrhosis.普萘洛尔降低曲张静脉压力:对肝硬化患者门静脉压力和奇静脉血流影响的比较
Hepatology. 1993 Nov;18(5):1082-9.
5
[Influence of the sclerosing of esophageal varices on portal pressure and azygos venous blood flow].[食管静脉曲张硬化对门静脉压力及奇静脉血流的影响]
Gastroenterol Clin Biol. 1990;14(3):244-7.
6
A pitfall in azygos vein cannulation in cirrhotic patients: mistaken cannulation of the mammary vein.
Angiology. 1990 Nov;41(11):942-5. doi: 10.1177/000331979004101108.
7
Measurement of azygos venous blood flow by a continuous thermal dilution technique: an index of blood flow through gastroesophageal collaterals in cirrhosis.
Hepatology. 1984 May-Jun;4(3):424-9. doi: 10.1002/hep.1840040312.
8
Superior portosystemic collateral circulation estimated by azygos blood flow in patients with cirrhosis. Lack of correlation with oesophageal varices and gastrointestinal bleeding. Effect of propranolol.
J Hepatol. 1985;1(1):37-46. doi: 10.1016/s0168-8278(85)80066-0.
9
[Correlation between hemodynamic parameters of the portal circulation in cirrhotic patients].[肝硬化患者门静脉循环血流动力学参数之间的相关性]
Gastroenterol Clin Biol. 1985 Oct;9(10):674-8.
10
[Blood flow and blood oxygen partial pressure of the azygos vein in portal hypertension evaluated by the catheter method].
Nihon Shokakibyo Gakkai Zasshi. 1991 Feb;88(2):145-52.

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1
Hemodynamic and metabolic effects of terlipressin in patients with cirrhosis receiving a nonselective beta-blocker.特利加压素对接受非选择性β受体阻滞剂治疗的肝硬化患者的血流动力学和代谢影响。
Dig Dis Sci. 1996 Sep;41(9):1722-6. doi: 10.1007/BF02088736.
2
Influence of the degree of liver failure on systemic and splanchnic haemodynamics and on response to propranolol in patients with cirrhosis.肝衰竭程度对肝硬化患者全身及内脏血流动力学以及对普萘洛尔反应的影响。
Gut. 1986 Oct;27(10):1204-9. doi: 10.1136/gut.27.10.1204.
3
Transcatheter embolization of liver capsule perforation during transvenous liver biopsy.
经静脉肝活检期间肝包膜穿孔的经导管栓塞术
Gastrointest Radiol. 1986;11(3):277-9. doi: 10.1007/BF02035089.