1 型糖尿病成人在热环境中进行有氧运动时循环鸢尾素迟钝：一项初步研究。
Blunted circulating irisin in adults with type 1 diabetes during aerobic exercise in a hot environment: a pilot study.
机构信息
Human and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Augustana Faculty, University of Alberta, Camrose, AB T4V 2R3, Canada.
出版信息
Appl Physiol Nutr Metab. 2020 Jun;45(6):679-682. doi: 10.1139/apnm-2019-0624. Epub 2020 Feb 13.
Irisin is a novel myokine associated with increased metabolism, which may be upregulated in type 1 diabetes (T1D) during exercise-heat stress. We therefore assessed serum irisin production in young adults with and without T1D during incremental exercise in dry-heat (35 °C). The change in irisin during exercise was lower in individuals with compared with without T1D (-1.79 (SEM 25.68) vs. 59.74 (SEM 79.63) pg/mL; = 0.024), indicating that irisin expression during exercise-heat stress is blunted in T1D. We show that, when assessed in young adults with and without T1D during exercise-heat stress, serum irisin production is blunted in T1D.
鸢尾素是一种与代谢增加相关的新型肌因子，在运动-热应激期间，1 型糖尿病 (T1D) 可能会上调。因此，我们在干热（35°C）下评估了有和没有 T1D 的年轻人在递增运动期间血清鸢尾素的产生。与没有 T1D 的个体相比，T1D 个体在运动期间鸢尾素的变化较低（-1.79（SEM 25.68）与 59.74（SEM 79.63）pg/mL；=0.024），表明 T1D 期间运动-热应激期间的鸢尾素表达减弱。我们表明，在运动-热应激期间评估有和没有 T1D 的年轻人时，T1D 中血清鸢尾素的产生减弱。
Zotero 插件