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斑状暗点见于近视性黄斑变性的脉络膜视网膜斑状萎缩。

Patchy Scotoma Observed in Chorioretinal Patchy Atrophy of Myopic Macular Degeneration.

机构信息

,.

出版信息

Invest Ophthalmol Vis Sci. 2020 Feb 7;61(2):15. doi: 10.1167/iovs.61.2.15.

DOI:10.1167/iovs.61.2.15
PMID:32053726
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7326503/
Abstract

PURPOSE

To investigate the retinal sensitivity of highly myopic eyes with chorioretinal patchy atrophy (PA) using microperimetry.

METHODS

Fifty-two eyes of 32 patients with high myopia were prospectively included. Twenty-two eyes of 16 patients had PA lesions; eyes without PA were analyzed as controls. Testing points on microperimetry in eyes with PA were designated as 3 zones: zone 1 as the PA lesion including its borders; zone 2 including testing points adjoining PA; zone 3 including all other testing points.

RESULTS

In the PA group, the mean retinal sensitivity in zone 1 was 2.1 ± 2.8 dB, zone 2 = 8.3 ± 4.3 dB, and zone 3 = 9.4 ± 4.1 dB. Sensitivity in zone 1 was significantly reduced than zones 2 and 3 (P < 0.001). The mean retinal sensitivity in the PA group was lower than controls (6.5 ± 4.3 vs 13.9 ± 4.1 dB, P < 0.001), and combined zone 2 and 3 in the PA group also presented lower retinal sensitivity (8.8 ± 4.0 dB).

CONCLUSIONS

Eyes with PA generate patchy scotoma in PA lesions and reduced retinal sensitivity in regions beyond atrophic lesion on microperimetry. The presence of PA may be an indicator to reflect both significantly anatomical and functional alterations on myopic macular degeneration.

摘要

目的

使用微视野计研究伴有脉络膜视网膜斑状萎缩（PA）的高度近视眼的视网膜敏感性。

方法

前瞻性纳入 32 名患者的 52 只高度近视眼。22 只眼有 PA 病变；无 PA 的眼作为对照进行分析。PA 眼的微视野计检测点被指定为 3 个区：区 1 为包括边界的 PA 病变；区 2 包括毗邻 PA 的检测点；区 3 包括所有其他检测点。

结果

在 PA 组中，区 1 的平均视网膜敏感性为 2.1 ± 2.8 dB，区 2 = 8.3 ± 4.3 dB，区 3 = 9.4 ± 4.1 dB。区 1 的敏感性明显低于区 2 和区 3（P < 0.001）。PA 组的平均视网膜敏感性低于对照组（6.5 ± 4.3 与 13.9 ± 4.1 dB，P < 0.001），PA 组的区 2 和区 3 联合敏感性也较低（8.8 ± 4.0 dB）。

结论

PA 眼在 PA 病变中产生斑状暗点，在微视野计上萎缩病变之外的区域视网膜敏感性降低。PA 的存在可能是反映近视性黄斑变性的显著解剖和功能改变的指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0238/7326503/2f3950279c75/iovs-61-2-15-f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0238/7326503/6bf53d56908a/iovs-61-2-15-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0238/7326503/4191365e21e7/iovs-61-2-15-f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0238/7326503/30005e53c2a8/iovs-61-2-15-f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0238/7326503/2f3950279c75/iovs-61-2-15-f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0238/7326503/6bf53d56908a/iovs-61-2-15-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0238/7326503/4191365e21e7/iovs-61-2-15-f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0238/7326503/30005e53c2a8/iovs-61-2-15-f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0238/7326503/2f3950279c75/iovs-61-2-15-f004.jpg

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